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T.thermophilus 30S ribosome with KsgA, class K2

Source organisms:
Biochemical function: rRNA binding
Biological process: translation
Cellular component: ribonucleoprotein complex

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EC 2.1.1.182: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase

Reaction catalysed:
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA
Systematic name:
S-adenosyl-L-methionine:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase
Alternative Name(s):
  • KsgA
  • KsgA methyltransferase
  • S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF17070
Domain description: 30S ribosomal protein Thx
Occurring in:
  1. Small ribosomal subunit protein bTHX
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF17070 (30S ribosomal protein Thx) in Small ribosomal subunit protein bTHX. Showing 1 copy in chain V.

PF00398
Domain description: Ribosomal RNA adenine dimethylase
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00398 (Ribosomal RNA adenine dimethylase) in Ribosomal RNA small subunit methyltransferase A. Showing 1 copy in chain U.

PF01649
Domain description: Ribosomal protein S20
Occurring in:
  1. Small ribosomal subunit protein bS20
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF01649 (Ribosomal protein S20) in Small ribosomal subunit protein bS20. Showing 1 copy in chain T.

PF00203
Domain description: Ribosomal protein S19
Occurring in:
  1. Small ribosomal subunit protein uS19
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00203 (Ribosomal protein S19) in Small ribosomal subunit protein uS19. Showing 1 copy in chain S.

PF01084
Domain description: Ribosomal protein S18
Occurring in:
  1. Small ribosomal subunit protein bS18
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF01084 (Ribosomal protein S18) in Small ribosomal subunit protein bS18. Showing 1 copy in chain R.

PF00366
Domain description: Ribosomal protein S17
Occurring in:
  1. Small ribosomal subunit protein uS17
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00366 (Ribosomal protein S17) in Small ribosomal subunit protein uS17. Showing 1 copy in chain Q.

PF00886
Domain description: Ribosomal protein S16
Occurring in:
  1. Small ribosomal subunit protein bS16
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00886 (Ribosomal protein S16) in Small ribosomal subunit protein bS16. Showing 1 copy in chain P.

PF00312
Domain description: Ribosomal protein S15
Occurring in:
  1. Small ribosomal subunit protein uS15
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00312 (Ribosomal protein S15) in Small ribosomal subunit protein uS15. Showing 1 copy in chain O.

PF00253
Domain description: Ribosomal protein S14p/S29e
Occurring in:
  1. Small ribosomal subunit protein uS14
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00253 (Ribosomal protein S14p/S29e) in Small ribosomal subunit protein uS14. Showing 1 copy in chain N.

PF00416
Domain description: Ribosomal protein S13/S18
Occurring in:
  1. Small ribosomal subunit protein uS13
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00416 (Ribosomal protein S13/S18) in Small ribosomal subunit protein uS13. Showing 1 copy in chain M.

PF00164
Domain description: Ribosomal protein S12/S23
Occurring in:
  1. Small ribosomal subunit protein uS12
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00164 (Ribosomal protein S12/S23) in Small ribosomal subunit protein uS12. Showing 1 copy in chain L.

PF00411
Domain description: Ribosomal protein S11
Occurring in:
  1. Small ribosomal subunit protein uS11
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00411 (Ribosomal protein S11) in Small ribosomal subunit protein uS11. Showing 1 copy in chain K.

PF00338
Domain description: Ribosomal protein S10p/S20e
Occurring in:
  1. Small ribosomal subunit protein uS10
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00338 (Ribosomal protein S10p/S20e) in Small ribosomal subunit protein uS10. Showing 1 copy in chain J.

PF00380
Domain description: Ribosomal protein S9/S16
Occurring in:
  1. Small ribosomal subunit protein uS9
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00380 (Ribosomal protein S9/S16) in Small ribosomal subunit protein uS9. Showing 1 copy in chain I.

PF00410
Domain description: Ribosomal protein S8
Occurring in:
  1. Small ribosomal subunit protein uS8
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00410 (Ribosomal protein S8) in Small ribosomal subunit protein uS8. Showing 1 copy in chain H.

PF00177
Domain description: Ribosomal protein S7p/S5e
Occurring in:
  1. Small ribosomal subunit protein uS7
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00177 (Ribosomal protein S7p/S5e) in Small ribosomal subunit protein uS7. Showing 1 copy in chain G.

PF01250
Domain description: Ribosomal protein S6
Occurring in:
  1. Small ribosomal subunit protein bS6
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF01250 (Ribosomal protein S6) in Small ribosomal subunit protein bS6. Showing 1 copy in chain F.

PF03719
Domain description: Ribosomal protein S5, C-terminal domain
Occurring in:
  1. Small ribosomal subunit protein uS5
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF03719 (Ribosomal protein S5, C-terminal domain) in Small ribosomal subunit protein uS5. Showing 1 copy in chain E.

PF00333
Domain description: Ribosomal protein S5, N-terminal domain
Occurring in:
  1. Small ribosomal subunit protein uS5
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00333 (Ribosomal protein S5, N-terminal domain) in Small ribosomal subunit protein uS5. Showing 1 copy in chain E.

PF01479
Domain description: S4 domain
Occurring in:
  1. Small ribosomal subunit protein uS4
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF01479 (S4 domain) in Small ribosomal subunit protein uS4. Showing 1 copy in chain D.

PF00163
Domain description: Ribosomal protein S4/S9 N-terminal domain
Occurring in:
  1. Small ribosomal subunit protein uS4
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00163 (Ribosomal protein S4/S9 N-terminal domain) in Small ribosomal subunit protein uS4. Showing 1 copy in chain D.

PF00189
Domain description: Ribosomal protein S3, C-terminal domain
Occurring in:
  1. Small ribosomal subunit protein uS3
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00189 (Ribosomal protein S3, C-terminal domain) in Small ribosomal subunit protein uS3. Showing 1 copy in chain C.

PF07650
Domain description: KH domain
Occurring in:
  1. Small ribosomal subunit protein uS3
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF07650 (KH domain) in Small ribosomal subunit protein uS3. Showing 1 copy in chain C.

PF00318
Domain description: Ribosomal protein S2
Occurring in:
  1. Small ribosomal subunit protein uS2
The deposited structure of PDB entry 7v2n contains 1 copy of Pfam domain PF00318 (Ribosomal protein S2) in Small ribosomal subunit protein uS2. Showing 1 copy in chain B.

Rfam RNA family (Rfam)
RF00177
Domain description: Bacterial small subunit ribosomal RNA
Occurring in:
  1. 16S ribosomal RNA
The deposited structure of PDB entry 7v2n contains 1 copy of Rfam domain RF00177 (Bacterial small subunit ribosomal RNA) in 16S ribosomal RNA. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001648
Domain description: Small ribosomal subunit protein bS18
Occurring in:
  1. Small ribosomal subunit protein bS18
IPR005679
Domain description: Ribosomal protein uS12, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS12
IPR001865
Domain description: Small ribosomal subunit protein uS2
Occurring in:
  1. Small ribosomal subunit protein uS2
IPR002222
Domain description: Small ribosomal subunit protein uS19
Occurring in:
  1. Small ribosomal subunit protein uS19
IPR000266
Domain description: Small ribosomal subunit protein uS17
Occurring in:
  1. Small ribosomal subunit protein uS17
IPR001848
Domain description: Small ribosomal subunit protein uS10
Occurring in:
  1. Small ribosomal subunit protein uS10
IPR002583
Domain description: Small ribosomal subunit protein bS20
Occurring in:
  1. Small ribosomal subunit protein bS20
IPR000307
Domain description: Small ribosomal subunit protein bS16
Occurring in:
  1. Small ribosomal subunit protein bS16
IPR001892
Domain description: Small ribosomal subunit protein uS13
Occurring in:
  1. Small ribosomal subunit protein uS13
IPR012340
Domain description: Nucleic acid-binding, OB-fold
Occurring in:
  1. Small ribosomal subunit protein uS12
  2. Small ribosomal subunit protein uS17
IPR006032
Domain description: Small ribosomal subunit protein uS12
Occurring in:
  1. Small ribosomal subunit protein uS12
IPR001971
Domain description: Small ribosomal subunit protein uS11
Occurring in:
  1. Small ribosomal subunit protein uS11
IPR001737
Domain description: Ribosomal RNA adenine methyltransferase KsgA/Erm
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
IPR000589
Domain description: Small ribosomal subunit protein uS15
Occurring in:
  1. Small ribosomal subunit protein uS15
IPR005290
Domain description: Small ribosomal subunit protein uS15, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS15
IPR000630
Domain description: Small ribosomal subunit protein uS8
Occurring in:
  1. Small ribosomal subunit protein uS8
IPR000529
Domain description: Small ribosomal subunit protein bS6
Occurring in:
  1. Small ribosomal subunit protein bS6
IPR005706
Domain description: Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid
Occurring in:
  1. Small ribosomal subunit protein uS2
IPR011530
Domain description: Ribosomal RNA adenine dimethylase
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
IPR029063
Domain description: S-adenosyl-L-methionine-dependent methyltransferase superfamily
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
IPR036510
Domain description: Small ribosomal subunit protein bS20 superfamily
Occurring in:
  1. Small ribosomal subunit protein bS20
IPR023575
Domain description: Small ribosomal subunit protein uS19, superfamily
Occurring in:
  1. Small ribosomal subunit protein uS19
IPR036870
Domain description: Small ribosomal subunit protein bS18 superfamily
Occurring in:
  1. Small ribosomal subunit protein bS18
IPR019984
Domain description: Small ribosomal subunit protein uS17, bacteria/chloroplast
Occurring in:
  1. Small ribosomal subunit protein uS17
IPR023803
Domain description: Small ribosomal subunit protein bS16 domain superfamily
Occurring in:
  1. Small ribosomal subunit protein bS16
IPR001209
Domain description: Small ribosomal subunit protein uS14
Occurring in:
  1. Small ribosomal subunit protein uS14
IPR036838
Domain description: Small ribosomal subunit protein uS10 domain superfamily
Occurring in:
  1. Small ribosomal subunit protein uS10
IPR000754
Domain description: Small ribosomal subunit protein uS9
Occurring in:
  1. Small ribosomal subunit protein uS9
IPR036823
Domain description: Small ribosomal subunit protein uS7 domain superfamily
Occurring in:
  1. Small ribosomal subunit protein uS7
IPR000235
Domain description: Small ribosomal subunit protein uS7
Occurring in:
  1. Small ribosomal subunit protein uS7
IPR005717
Domain description: Small ribosomal subunit protein uS7, bacterial/organellar-type
Occurring in:
  1. Small ribosomal subunit protein uS7
IPR020814
Domain description: Small ribosomal subunit protein bS6, plastid/chloroplast
Occurring in:
  1. Small ribosomal subunit protein bS6
IPR014717
Domain description: Translation elongation factor EF1B/small ribosomal subunit protein bS6
Occurring in:
  1. Small ribosomal subunit protein bS6
IPR020568
Domain description: Ribosomal protein uS5 domain 2-type superfamily
Occurring in:
  1. Small ribosomal subunit protein uS5
  2. Small ribosomal subunit protein uS9
IPR014721
Domain description: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Occurring in:
  1. Small ribosomal subunit protein uS5
  2. Small ribosomal subunit protein uS9
IPR013810
Domain description: Small ribosomal subunit protein uS5, N-terminal
Occurring in:
  1. Small ribosomal subunit protein uS5
IPR005712
Domain description: Small ribosomal subunit protein uS5, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS5
IPR002942
Domain description: RNA-binding S4 domain
Occurring in:
  1. Small ribosomal subunit protein uS4
IPR005709
Domain description: Small ribosomal subunit protein uS4, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS4
IPR036419
Domain description: Ribosomal protein S3, C-terminal domain superfamily
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR004044
Domain description: K Homology domain, type 2
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR005704
Domain description: Small ribosomal subunit protein uS3, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR031414
Domain description: Small ribosomal subunit protein bTHX
Occurring in:
  1. Small ribosomal subunit protein bTHX
IPR030826
Domain description: Small ribosomal subunit protein bTHX/bTHXc/bTHXm
Occurring in:
  1. Small ribosomal subunit protein bTHX
IPR023165
Domain description: rRNA adenine dimethylase-like, C-terminal
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
IPR020596
Domain description: Ribosomal RNA adenine methylase transferase, conserved site
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
IPR020598
Domain description: Ribosomal RNA adenine methylase transferase, N-terminal
Occurring in:
  1. Ribosomal RNA small subunit methyltransferase A
IPR020934
Domain description: Small ribosomal subunit protein uS19, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS19
IPR005732
Domain description: Small ribosomal subunit protein uS19, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS19
IPR018275
Domain description: Small ribosomal subunit protein bS18, conserved site
Occurring in:
  1. Small ribosomal subunit protein bS18
IPR019979
Domain description: Small ribosomal subunit protein uS17, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS17
IPR009068
Domain description: uS15/NS1, RNA-binding domain superfamily
Occurring in:
  1. Small ribosomal subunit protein uS15
IPR018271
Domain description: Small ribosomal subunit protein uS14, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS14
IPR043140
Domain description: Small ribosomal subunit protein uS14 superfamily
Occurring in:
  1. Small ribosomal subunit protein uS14
IPR023053
Domain description: Small ribosomal subunit protein uS14, bacteria
Occurring in:
  1. Small ribosomal subunit protein uS14
IPR018269
Domain description: Small ribosomal subunit protein uS13, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS13
IPR027437
Domain description: Small ribosomal subunit protein uS13, C-terminal
Occurring in:
  1. Small ribosomal subunit protein uS13
IPR019980
Domain description: Small ribosomal subunit protein uS13, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS13
IPR010979
Domain description: Small ribosomal subunit protein uS13-like, H2TH
Occurring in:
  1. Small ribosomal subunit protein uS13
IPR018102
Domain description: Small ribosomal subunit protein uS11, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS11
IPR019981
Domain description: Small ribosomal subunit protein uS11, bacterial-type
Occurring in:
  1. Small ribosomal subunit protein uS11
IPR036967
Domain description: Small ribosomal subunit protein uS11 superfamily
Occurring in:
  1. Small ribosomal subunit protein uS11
IPR018268
Domain description: Small ribosomal subunit protein uS10, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS10
IPR027486
Domain description: Small ribosomal subunit protein uS10 domain
Occurring in:
  1. Small ribosomal subunit protein uS10
IPR020574
Domain description: Small ribosomal subunit protein uS9, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS9
IPR023035
Domain description: Small ribosomal subunit protein uS9, bacterial/plastid
Occurring in:
  1. Small ribosomal subunit protein uS9
IPR047863
Domain description: Small ribosomal subunit protein uS8, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS8
IPR035987
Domain description: Small ribosomal subunit protein uS8 superfamily
Occurring in:
  1. Small ribosomal subunit protein uS8
IPR020606
Domain description: Small ribosomal subunit protein uS7, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS7
IPR023798
Domain description: Small ribosomal subunit protein uS7 domain
Occurring in:
  1. Small ribosomal subunit protein uS7
IPR020815
Domain description: Small ribosomal subunit protein bS6, conserved site
Occurring in:
  1. Small ribosomal subunit protein bS6
IPR035980
Domain description: Small ribosomal subunit protein bS6 superfamily
Occurring in:
  1. Small ribosomal subunit protein bS6
IPR005324
Domain description: Small ribosomal subunit protein uS5, C-terminal
Occurring in:
  1. Small ribosomal subunit protein uS5
IPR018192
Domain description: Small ribosomal subunit protein uS5, N-terminal, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS5
IPR000851
Domain description: Small ribosomal subunit protein uS5
Occurring in:
  1. Small ribosomal subunit protein uS5
IPR036986
Domain description: RNA-binding S4 domain superfamily
Occurring in:
  1. Small ribosomal subunit protein uS4
IPR018079
Domain description: Small ribosomal subunit protein uS4, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS4
IPR022801
Domain description: Small ribosomal subunit protein uS4
Occurring in:
  1. Small ribosomal subunit protein uS4
IPR001912
Domain description: Small ribosomal subunit protein uS4, N-terminal
Occurring in:
  1. Small ribosomal subunit protein uS4
IPR018280
Domain description: Small ribosomal subunit protein uS3, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR001351
Domain description: Small ribosomal subunit protein uS3, C-terminal
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR004087
Domain description: K Homology domain
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR015946
Domain description: K homology domain-like, alpha/beta
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR009019
Domain description: K homology domain superfamily, prokaryotic type
Occurring in:
  1. Small ribosomal subunit protein uS3
IPR023591
Domain description: Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily
Occurring in:
  1. Small ribosomal subunit protein uS2
IPR018130
Domain description: Small ribosomal subunit protein uS2, conserved site
Occurring in:
  1. Small ribosomal subunit protein uS2

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