Function and Biology

Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)

Source organism: Mus musculus
Biochemical function: hedgehog receptor activity
Biological process: not assigned
Cellular component: membrane

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF02460
Domain description: Patched family
Occurring in:
  1. Protein patched homolog 1
The deposited structure of PDB entry 7v6y contains 1 copy of Pfam domain PF02460 (Patched family) in Protein patched homolog 1. Showing 1 copy in chain A.

PF12349
Domain description: Sterol-sensing domain of SREBP cleavage-activation
Occurring in:
  1. Protein patched homolog 1
The deposited structure of PDB entry 7v6y contains 1 copy of Pfam domain PF12349 (Sterol-sensing domain of SREBP cleavage-activation) in Protein patched homolog 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003392
Domain description: Protein patched/dispatched
Occurring in:
  1. Protein patched homolog 1
IPR000731
Domain description: Sterol-sensing domain
Occurring in:
  1. Protein patched homolog 1
IPR004766
Domain description: Transmembrane receptor, patched
Occurring in:
  1. Protein patched homolog 1