› › Structure analysis

human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic agonist JKPL39

X-ray diffraction
2.1Å resolution
PDB entry 7vwh coloured by chain, front view.
PDB entry 7vwh coloured by chain, side view.
PDB entry 7vwh coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Peroxisome proliferator-activated receptor delta
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 23818.93 Å2
Buried surface area: 2753.24 Å2
Dissociation area: 1,114.78 Å2
Dissociation energy (ΔGdiss): 1.24 kcal/mol
Dissociation entropy (TΔSdiss): 13.23 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-169864

Macromolecules

Peroxisome proliferator-activated receptor delta
Chains: A, B
Length: 276 amino acids
Theoretical weight: 31.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03181 (Residues: 170-441; Coverage: 62%)
Gene names: NR1C2, PPARB, PPARD
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
Peroxisome proliferator-activated receptor delta in PDB entry 7vwh, assembly 1, front view.
Peroxisome proliferator-activated receptor delta in PDB entry 7vwh, assembly 1, side view.
Peroxisome proliferator-activated receptor delta in PDB entry 7vwh, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q03181  
Loading Protvista...
Molecule details ›

Search similar proteins

Quick links