Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Processed angiotensin-converting enzyme 2
Molecule details ›
Chain: A
Length: 625 amino acids
Theoretical weight: 72.4 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 625 amino acids
Theoretical weight: 72.4 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9BYF1 (Residues: 17-615; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Spike protein S1
Molecule details ›
Chain: E
Length: 194 amino acids
Theoretical weight: 21.85 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Length: 194 amino acids
Theoretical weight: 21.85 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
- Canonical: P0DTC2 (Residues: 333-526; Coverage: 15%)
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
