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SARS-CoV-2 Delta S-RBD-ACE2

Source organism: Severe acute respiratory syndrome-related coronavirus
Biochemical function: peptidyl-dipeptidase activity
Biological process: proteolysis
Cellular component: membrane

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EC 3.4.17.23: Angiotensin-converting enzyme 2

Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Systematic name:
-
Alternative Name(s):
  • ACE-2
  • ACE2
  • Angiotensin converting enzyme 2
  • Angiotensin converting enzyme-2
  • HACE2
  • Tmem27

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF09408
Domain description: Betacoronavirus spike glycoprotein S1, receptor binding
Occurring in:
  1. Spike protein S1
The deposited structure of PDB entry 7w9i contains 1 copy of Pfam domain PF09408 (Betacoronavirus spike glycoprotein S1, receptor binding) in Spike protein S1. Showing 1 copy in chain B [auth E].

PF01401
Domain description: Angiotensin-converting enzyme
Occurring in:
  1. Processed angiotensin-converting enzyme 2
The deposited structure of PDB entry 7w9i contains 1 copy of Pfam domain PF01401 (Angiotensin-converting enzyme) in Processed angiotensin-converting enzyme 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001548
Domain description: Peptidase M2, peptidyl-dipeptidase A
Occurring in:
  1. Processed angiotensin-converting enzyme 2
IPR018548
Domain description: Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus
Occurring in:
  1. Spike protein S1
IPR036326
Domain description: Spike S1 subunit, receptor binding domain superfamily, betacoronavirus
Occurring in:
  1. Spike protein S1

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