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Cryo-EM structure of Drg1 hexamer treated with ATP and benzo-diazaborine

Source organism: Saccharomyces cerevisiae
Biochemical function: ATP hydrolysis activity
Biological process: ribosomal large subunit biogenesis
Cellular component: preribosome, large subunit precursor

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EC 3.6.4.10: Non-chaperonin molecular chaperone ATPase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (polypeptide-polymerizing)
Alternative Name(s):
  • Molecular chaperone Hsc70 ATPase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF17862
Domain description: AAA+ lid domain
Occurring in:
  1. ATPase family gene 2 protein
The deposited structure of PDB entry 7wd3 contains 12 copies of Pfam domain PF17862 (AAA+ lid domain) in ATPase family gene 2 protein. Showing 2 copies in chain A.

PF00004
Domain description: ATPase family associated with various cellular activities (AAA)
Occurring in:
  1. ATPase family gene 2 protein
The deposited structure of PDB entry 7wd3 contains 12 copies of Pfam domain PF00004 (ATPase family associated with various cellular activities (AAA)) in ATPase family gene 2 protein. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. ATPase family gene 2 protein
IPR041569
Domain description: AAA ATPase, AAA+ lid domain
Occurring in:
  1. ATPase family gene 2 protein
IPR003960
Domain description: ATPase, AAA-type, conserved site
Occurring in:
  1. ATPase family gene 2 protein
IPR003959
Domain description: ATPase, AAA-type, core
Occurring in:
  1. ATPase family gene 2 protein
IPR003593
Domain description: AAA+ ATPase domain
Occurring in:
  1. ATPase family gene 2 protein

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