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The 0.83 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with nervonic acid

X-ray diffraction
0.83Å resolution
PDB entry 7wf0 coloured by chain, front view.
PDB entry 7wf0 coloured by chain, side view.
PDB entry 7wf0 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fatty acid-binding protein, heart
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Multimeric state: monomeric
Accessible surface area: 7300.64 Å2
Buried surface area: 1426.65 Å2
Dissociation area: 488.09 Å2
Dissociation energy (ΔGdiss): -8.51 kcal/mol
Dissociation entropy (TΔSdiss): 4.73 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138660

Macromolecules

Fatty acid-binding protein, heart
Chain: A
Length: 133 amino acids
Theoretical weight: 14.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05413 (Residues: 1-133; Coverage: 100%)
Gene names: FABP11, FABP3, MDGI
Pfam: Lipocalin / cytosolic fatty-acid binding protein family
InterPro:
Fatty acid-binding protein, heart in PDB entry 7wf0, assembly 1, front view.
Fatty acid-binding protein, heart in PDB entry 7wf0, assembly 1, side view.
Fatty acid-binding protein, heart in PDB entry 7wf0, assembly 1, top view.
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