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RBD in complex with Fab14

Electron Microscopy
7.3Å resolution
PDB entry 7xxl coloured by chain, front view.
PDB entry 7xxl coloured by chain, side view.
PDB entry 7xxl coloured by chain, top view.
Source organisms:
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 29540.7 Å2
Buried surface area: 4129.67 Å2
Dissociation area: 320.13 Å2
Dissociation energy (ΔGdiss): -8.35 kcal/mol
Dissociation entropy (TΔSdiss): 12.61 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-225147

Macromolecules

Fab14 light chain
Chain: C
Length: 213 amino acids
Theoretical weight: 22.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
InterPro:
Fab14 light chain in PDB entry 7xxl, assembly 1, front view.
Fab14 light chain in PDB entry 7xxl, assembly 1, side view.
Fab14 light chain in PDB entry 7xxl, assembly 1, top view.
Molecule details ›

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Immunoglobulin gamma-1 heavy chain
Chain: A
Length: 235 amino acids
Theoretical weight: 25.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DOX5 (Residues: 1-34, 35-56, 57-98, 99-108, 109-226; Coverage: 50%)
Pfam:
InterPro:
Immunoglobulin gamma-1 heavy chain in PDB entry 7xxl, assembly 1, front view.
Immunoglobulin gamma-1 heavy chain in PDB entry 7xxl, assembly 1, side view.
Immunoglobulin gamma-1 heavy chain in PDB entry 7xxl, assembly 1, top view.
Molecule details ›

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Spike protein S1
Chain: B
Length: 204 amino acids
Theoretical weight: 22.82 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 331-532; Coverage: 16%)
Gene names: 2, S
Pfam: Betacoronavirus spike glycoprotein S1, receptor binding
InterPro:
Spike protein S1 in PDB entry 7xxl, assembly 1, front view.
Spike protein S1 in PDB entry 7xxl, assembly 1, side view.
Spike protein S1 in PDB entry 7xxl, assembly 1, top view.
Molecule details ›

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