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The pre-fusion structure of Thogotovirus dhori envelope glycoprotein

Electron Microscopy
3.3Å resolution
PDB entry 7xym coloured by chain, front view.
PDB entry 7xym coloured by chain, side view.
PDB entry 7xym coloured by chain, top view.
Source organism: Dhori thogotovirus
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Envelope glycoprotein
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Multimeric state: homo trimer
Accessible surface area: 69044.73 Å2
Buried surface area: 39702.67 Å2
Dissociation area: 19,851.33 Å2
Dissociation energy (ΔGdiss): 311.86 kcal/mol
Dissociation entropy (TΔSdiss): 35.38 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-151000

Macromolecules

Envelope glycoprotein
Chains: A, B, C
Length: 520 amino acids
Theoretical weight: 58.67 KDa
Source organism: Dhori thogotovirus
Expression system: Homo sapiens
UniProt:
  • Canonical: P27427 (Residues: 2-521; Coverage: 100%)
Gene name: P4
Pfam: Baculovirus gp64 envelope glycoprotein family
Envelope glycoprotein in PDB entry 7xym, assembly 1, front view.
Envelope glycoprotein in PDB entry 7xym, assembly 1, side view.
Envelope glycoprotein in PDB entry 7xym, assembly 1, top view.
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