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Crystal structure of sDscam FNIII3 domain, isoform alpha7

X-ray diffraction
1.9Å resolution
PDB entry 7y8i coloured by chain, front view.
PDB entry 7y8i coloured by chain, side view.
PDB entry 7y8i coloured by chain, top view.
Source organism: Chelicerata
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1
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Assembly Name: Dscam
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Multimeric state: monomeric
Accessible surface area: 5204.09 Å2
Buried surface area: 121.41 Å2
Dissociation area: 60.7 Å2
Dissociation energy (ΔGdiss): 2.9 kcal/mol
Dissociation entropy (TΔSdiss): 0.62 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-216096
Assembly 2
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Assembly Name: Dscam
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Multimeric state: monomeric
Accessible surface area: 5657.01 Å2
Buried surface area: 466.77 Å2
Dissociation area: 100.32 Å2
Dissociation energy (ΔGdiss): -3.08 kcal/mol
Dissociation entropy (TΔSdiss): 0.02 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-216096
Assembly 3
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Assembly Name: Dscam
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Multimeric state: monomeric
Accessible surface area: 5532.39 Å2
Buried surface area: 199.52 Å2
Dissociation area: 99.76 Å2
Dissociation energy (ΔGdiss): -3.88 kcal/mol
Dissociation entropy (TΔSdiss): 0.03 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-216096
Assembly 4
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Assembly Name: Dscam
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Multimeric state: monomeric
Accessible surface area: 5925.33 Å2
Buried surface area: 173.93 Å2
Dissociation area: 86.97 Å2
Dissociation energy (ΔGdiss): 4.81 kcal/mol
Dissociation entropy (TΔSdiss): 0.62 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-216096
Assembly 5
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Assembly Name: Dscam
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Multimeric state: monomeric
Accessible surface area: 6571.0 Å2
Buried surface area: 337.07 Å2
Dissociation area: 54.86 Å2
Dissociation energy (ΔGdiss): 3.1 kcal/mol
Dissociation entropy (TΔSdiss): 0.61 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-216096
Assembly 6 (preferred)
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Assembly Name: Dscam
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Multimeric state: monomeric
Accessible surface area: 5537.1 Å2
Buried surface area: 467.89 Å2
Dissociation area: 93.46 Å2
Dissociation energy (ΔGdiss): -4.28 kcal/mol
Dissociation entropy (TΔSdiss): 1.45 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-216096

Macromolecules

Dscam
Chains: A, B, C, D, E, F
Length: 97 amino acids
Theoretical weight: 10.92 KDa
Source organism: Chelicerata
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A159W468 (Residues: 492-588; Coverage: 13%)
Gene name: Dscam
Pfam: Fibronectin type III domain
Dscam in PDB entry 7y8i, assembly 6, front view.
Dscam in PDB entry 7y8i, assembly 6, side view.
Dscam in PDB entry 7y8i, assembly 6, top view.
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