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Structure of Serine-Threonine kinase STK25 in complex with compound

X-ray diffraction
1.644Å resolution
PDB entry 7z4v coloured by chain, front view.
PDB entry 7z4v coloured by chain, side view.
PDB entry 7z4v coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serine/threonine-protein kinase 25
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Multimeric state: monomeric
Accessible surface area: 14086.9 Å2
Buried surface area: 237.19 Å2
Dissociation area: 118.59 Å2
Dissociation energy (ΔGdiss): -3.86 kcal/mol
Dissociation entropy (TΔSdiss): 0.05 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-126324

Macromolecules

Serine/threonine-protein kinase 25
Chain: A
Length: 297 amino acids
Theoretical weight: 33.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00506 (Residues: 1-294; Coverage: 69%)
Gene names: SOK1, STK25, YSK1
Pfam: Protein kinase domain
InterPro:
Serine/threonine-protein kinase 25 in PDB entry 7z4v, assembly 1, front view.
Serine/threonine-protein kinase 25 in PDB entry 7z4v, assembly 1, side view.
Serine/threonine-protein kinase 25 in PDB entry 7z4v, assembly 1, top view.
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