Function and Biology

Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody

Source organisms:
Biochemical function: glycosyltransferase activity
Biological process: cell differentiation
Cellular component: extracellular region

Sequence families

Pfam Protein families (Pfam)
PF07654
Domain description: Immunoglobulin C1-set domain
Occurring in:
  1. Ig-like domain-containing protein
The deposited structure of PDB entry 7zli contains 1 copy of Pfam domain PF07654 (Immunoglobulin C1-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain C [auth L].

PF07686
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Ig-like domain-containing protein
The deposited structure of PDB entry 7zli contains 1 copy of Pfam domain PF07686 (Immunoglobulin V-set domain) in Ig-like domain-containing protein. Showing 1 copy in chain C [auth L].

PF10034
Domain description: Q-cell neuroblast polarisation
Occurring in:
  1. C-mannosyltransferase dpy-19
The deposited structure of PDB entry 7zli contains 1 copy of Pfam domain PF10034 (Q-cell neuroblast polarisation) in C-mannosyltransferase dpy-19. Showing 1 copy in chain D [auth A].

InterPro InterPro annotations
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. CMT2-Fab heavy chain
  2. Anti-Fab nanobody
  3. Ig-like domain-containing protein
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. CMT2-Fab heavy chain
  2. Anti-Fab nanobody
  3. Ig-like domain-containing protein
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. CMT2-Fab heavy chain
  2. Anti-Fab nanobody
  3. Ig-like domain-containing protein
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. CMT2-Fab heavy chain
  2. Anti-Fab nanobody
  3. Ig-like domain-containing protein
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. CMT2-Fab heavy chain
  2. Ig-like domain-containing protein
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. CMT2-Fab heavy chain
  2. Anti-Fab nanobody
  3. Ig-like domain-containing protein
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. CMT2-Fab heavy chain
  2. Ig-like domain-containing protein
IPR018732
Domain description: Dpy-19/Dpy-19-like
Occurring in:
  1. C-mannosyltransferase dpy-19
IPR011330
Domain description: Glycoside hydrolase/deacetylase, beta/alpha-barrel
Occurring in:
  1. C-mannosyltransferase dpy-19
IPR047462
Domain description: C-mannosyltransferase Dpy19
Occurring in:
  1. C-mannosyltransferase dpy-19