Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Heat shock protein Hsp90, N-terminal
- Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
- Heat shock protein Hsp90 family
- Diacylglycerol/phorbol-ester binding
- HSP90, C-terminal domain
- Histidine kinase/HSP90-like ATPase domain
- Histidine kinase/HSP90-like ATPase superfamily
- Tetratricopeptide repeat
21 more domains
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-140051 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Heat shock protein HSP 90-beta
Molecule details ›
Hsp90 co-chaperone Cdc37
Molecule details ›
Chain: C
Length: 396 amino acids
Theoretical weight: 46.85 KDa
Source organism: Homo sapiens
Expression system: Spodoptera
UniProt:
Sequence domains:
Length: 396 amino acids
Theoretical weight: 46.85 KDa
Source organism: Homo sapiens
Expression system: Spodoptera
UniProt:
- Canonical:
Q16543 (Residues: 1-378; Coverage: 100%)
Sequence domains:
Serine/threonine-protein kinase B-raf
Serine/threonine-protein phosphatase 5
