› 7zsq

X-ray diffraction
1.77Å resolution

Function and Biology Details

Reaction catalysed: 
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161909 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Purine nucleoside phosphorylase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 269 amino acids
Theoretical weight: 27.72 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WP01 (Residues: 2-268; Coverage: 100%)
Gene names: MTV016.06, Rv3307, deoD, punA
Sequence domains: Phosphorylase superfamily

Ligands and Environments

6 bound ligands:
Ligand JTO 3 x JTO
Ligand TEW 1 x TEW
Ligand GOL 1 x GOL
Ligand P4K 1 x P4K
Ligand EDO 1 x EDO
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 57.07Å b: 90.93Å c: 143.07Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.214
Expression system: Escherichia coli

Quick links

Citations

2 mentions without citation

A Comprehensive Structural Analysis of Clostridium botulinum Neurotoxin A Cell-Binding Domain from Different Subtypes.
Gregory et al. (2023)
1 more