› › Structure analysis

human purine nucleoside phosphorylase in complex with JS-555

X-ray diffraction
1.77Å resolution
PDB entry 7zsq coloured by chain, front view.
PDB entry 7zsq coloured by chain, side view.
PDB entry 7zsq coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Purine nucleoside phosphorylase
hide full assembly name
Multimeric state: homo trimer
Accessible surface area: 28022.16 Å2
Buried surface area: 6057.79 Å2
Dissociation area: 2,912.65 Å2
Dissociation energy (ΔGdiss): 22.61 kcal/mol
Dissociation entropy (TΔSdiss): 26.82 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-161909

Macromolecules

Purine nucleoside phosphorylase
Chains: A, B, C
Length: 269 amino acids
Theoretical weight: 27.72 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WP01 (Residues: 2-268; Coverage: 100%)
Gene names: MTV016.06, Rv3307, deoD, punA
Pfam: Phosphorylase superfamily
Purine nucleoside phosphorylase in PDB entry 7zsq, assembly 1, front view.
Purine nucleoside phosphorylase in PDB entry 7zsq, assembly 1, side view.
Purine nucleoside phosphorylase in PDB entry 7zsq, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links