8t2v

Electron Microscopy
3.4Å resolution

Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids

Released:
Source organism: Homo sapiens
Related structures: EMD-40989

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138441 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (6 distinct):
Integrin alpha-IIb Chain: A
Molecule details ›
Chain: A
Length: 1008 amino acids
Theoretical weight: 110.11 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08514 (Residues: 32-1039; Coverage: 100%)
Gene names: GP2B, ITGA2B, ITGAB
Sequence domains:
Integrin beta-3 Chain: B
Molecule details ›
Chain: B
Length: 762 amino acids
Theoretical weight: 84.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05106 (Residues: 27-788; Coverage: 100%)
Gene names: GP3A, ITGB3
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-40989