› 8ttz

X-ray diffraction
3.14Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109967 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
TIR domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 817 amino acids
Theoretical weight: 94.01 KDa
Source organism: Macaca mulatta
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: B3Y653 (Residues: 27-839; Coverage: 78%)
Gene name: TLR7
Sequence domains: Leucine rich repeat

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand NAG 12 x NAG
Ligand SO4 29 x SO4
Ligand QCX 2 x QCX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 97.805Å b: 138.691Å c: 148.671Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.241
Expression system: Drosophila melanogaster

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