8x93

Electron Microscopy
2.92Å resolution

P/Q type calcium channel in complex with omega-Agatoxin IVA

Released:

Function and Biology Details

Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-241858 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
Voltage-dependent L-type calcium channel subunit beta-3 Chain: C
Molecule details ›
Chain: C
Length: 496 amino acids
Theoretical weight: 56.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P54284 (Residues: 1-484; Coverage: 100%)
Gene names: CACNB3, CACNLB3
Sequence domains:
Voltage-dependent calcium channel subunit alpha-2/delta-1 Chain: B
Molecule details ›
Chain: B
Length: 1115 amino acids
Theoretical weight: 126.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P54289 (Residues: 1-1103; Coverage: 100%)
Gene names: CACNA2D1, CACNL2A, CCHL2A, MHS3
Sequence domains:
Voltage-dependent P/Q-type calcium channel subunit alpha-1A Chain: A
Molecule details ›
Chain: A
Length: 2549 amino acids
Theoretical weight: 287.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O00555 (Residues: 1-2506; Coverage: 100%)
Gene names: CACH4, CACN3, CACNA1A, CACNL1A4
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.92Å
Relevant EMDB volumes: EMD-38160
Expression system: Homo sapiens