Assemblies
Assembly Name:
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 and Serine protease HTRA2, mitochondrial
Multimeric state:
hetero pentamer
Accessible surface area:
258123.0 Å2
Buried surface area:
24728.65 Å2
Dissociation area:
981.95
Å2
Dissociation energy (ΔGdiss):
-10.27
kcal/mol
Dissociation entropy (TΔSdiss):
15.39
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-128935
Macromolecules
Chains: A, B
Length: 4867 amino acids
Theoretical weight: 532.01 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Pfam:
Length: 4867 amino acids
Theoretical weight: 532.01 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q9NR09 (Residues: 1-4857; Coverage: 100%)
Pfam:
- Inhibitor of Apoptosis domain
- Baculoviral IAP repeat-containing protein 6
- Ubiquitin-conjugating enzyme
PDBe-KB: UniProt Coverage View:
Q9NR09
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Chains: C, D, E
Length: 325 amino acids
Theoretical weight: 35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 325 amino acids
Theoretical weight: 35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O43464 (Residues: 134-458; Coverage: 71%)
Pfam:
InterPro:
PDBe-KB: UniProt Coverage View:
O43464
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