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Unliganded transcriptional pleiotropic repressor CodY from Enterococcus faecalis

X-ray diffraction
2.21Å resolution
PDB entry 8c7t coloured by chain, front view.
PDB entry 8c7t coloured by chain, side view.
PDB entry 8c7t coloured by chain, top view.
Source organism: Enterococcus faecalis V583
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Global transcriptional regulator CodY
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Multimeric state: homo dimer
Accessible surface area: 27635.78 Å2
Buried surface area: 4029.22 Å2
Dissociation area: 2,014.61 Å2
Dissociation energy (ΔGdiss): 33.13 kcal/mol
Dissociation entropy (TΔSdiss): 13.62 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-218819
Assembly 2
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Assembly Name: Global transcriptional regulator CodY
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Multimeric state: homo dimer
Accessible surface area: 23460.69 Å2
Buried surface area: 3957.97 Å2
Dissociation area: 1,978.98 Å2
Dissociation energy (ΔGdiss): 33.46 kcal/mol
Dissociation entropy (TΔSdiss): 12.93 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-218819

Macromolecules

Global transcriptional regulator CodY
Chains: A, B, C, D
Length: 262 amino acids
Theoretical weight: 29.08 KDa
Source organism: Enterococcus faecalis V583
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1B4XP18 (Residues: 1-260; Coverage: 100%)
Gene names: DAI13_08275, EY666_04655, GTI81_07970, H9Q64_02750, NCTC13379_02184, P0E79_01400, codY
Pfam:
Global transcriptional regulator CodY in PDB entry 8c7t, assembly 1, front view.
Global transcriptional regulator CodY in PDB entry 8c7t, assembly 1, side view.
Global transcriptional regulator CodY in PDB entry 8c7t, assembly 1, top view.
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