› › Structure analysis

Crystal structure of human DNA cross-link repair 1A in complex with a cyclic N-hydroxyurea inhibitor

X-ray diffraction
1.68Å resolution
PDB entry 8cg9 coloured by chain, front view.
PDB entry 8cg9 coloured by chain, side view.
PDB entry 8cg9 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: DNA cross-link repair 1A protein
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 14973.42 Å2
Buried surface area: 337.73 Å2
Dissociation area: 18.63 Å2
Dissociation energy (ΔGdiss): 9.49 kcal/mol
Dissociation entropy (TΔSdiss): -0.13 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-180185

Macromolecules

DNA cross-link repair 1A protein
Chain: A
Length: 345 amino acids
Theoretical weight: 39.14 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q6PJP8 (Residues: 696-1040; Coverage: 33%)
Gene names: DCLRE1A, KIAA0086, SNM1, SNM1A
Pfam: DNA repair metallo-beta-lactamase
DNA cross-link repair 1A protein in PDB entry 8cg9, assembly 1, front view.
DNA cross-link repair 1A protein in PDB entry 8cg9, assembly 1, side view.
DNA cross-link repair 1A protein in PDB entry 8cg9, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links