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Crystal structure of a four-tetrad, parallel, and Na+ stabilized Tetrahymena thermophila telomeric G-quadruplex in complex with N-methyl mesoporphyrin IX

X-ray diffraction
1.99Å resolution
PDB entry 8d79 coloured by chain, front view.
PDB entry 8d79 coloured by chain, side view.
PDB entry 8d79 coloured by chain, top view.
Source organism: Tetrahymena thermophila
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct DNA molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: DNA
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Multimeric state: monomeric
Accessible surface area: 4671.72 Å2
Buried surface area: 1408.89 Å2
Dissociation area: 272.89 Å2
Dissociation energy (ΔGdiss): -6.79 kcal/mol
Dissociation entropy (TΔSdiss): 4.91 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-219809

Macromolecules

DNA chain A
Name: DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3')
Representative chains: A
Source organism: Tetrahymena thermophila [5911]
Expression system: Not provided
Length: 24 nucleotides
Theoretical weight: 7.66 KDa
DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3') in PDB entry 8d79, assembly 1, front view.
DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3') in PDB entry 8d79, assembly 1, side view.
DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3') in PDB entry 8d79, assembly 1, top view.
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