Function and Biology

Rabbit L-type voltage-gated calcium channel Cav1.1 in the presence of Amiodarone and 1 mM MNI-1 at 3.0 Angstrom resolution

Source organism: Oryctolagus cuniculus
Biochemical function: protein binding
Biological process: calcium ion transmembrane transport
Cellular component: L-type voltage-gated calcium channel complex

Sequence families

Pfam Protein families (Pfam)
PF00520
Domain description: Ion transport protein
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
The deposited structure of PDB entry 8e58 contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Voltage-dependent L-type calcium channel subunit alpha-1S. Showing 4 copies in chain A.

PF08016
Domain description: Polycystin cation channel
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
The deposited structure of PDB entry 8e58 contains 2 copies of Pfam domain PF08016 (Polycystin cation channel) in Voltage-dependent L-type calcium channel subunit alpha-1S. Showing 2 copies in chain A.

PF08473
Domain description: Neuronal voltage-dependent calcium channel alpha 2acd
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF08473 (Neuronal voltage-dependent calcium channel alpha 2acd) in Voltage-dependent calcium channel subunit alpha-2/delta-1. Showing 1 copy in chain C [auth F].

PF00092
Domain description: von Willebrand factor type A domain
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF00092 (von Willebrand factor type A domain) in Voltage-dependent calcium channel subunit alpha-2/delta-1. Showing 1 copy in chain C [auth F].

PF08399
Domain description: VWA N-terminal
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF08399 (VWA N-terminal) in Voltage-dependent calcium channel subunit alpha-2/delta-1. Showing 1 copy in chain C [auth F].

PF13903
Domain description: PMP-22/EMP/MP20/Claudin tight junction
Occurring in:
  1. Voltage-dependent calcium channel gamma-1 subunit
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF13903 (PMP-22/EMP/MP20/Claudin tight junction) in Voltage-dependent calcium channel gamma-1 subunit. Showing 1 copy in chain B [auth E].

PF16885
Domain description: Voltage-gated calcium channel subunit alpha, C-term
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF16885 (Voltage-gated calcium channel subunit alpha, C-term) in Voltage-dependent L-type calcium channel subunit alpha-1S. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF08763
Domain description: Voltage gated calcium channel IQ domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF08763 (Voltage gated calcium channel IQ domain) in Voltage-dependent L-type calcium channel subunit alpha-1S. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF16905
Domain description: Voltage-dependent L-type calcium channel, IQ-associated
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
The deposited structure of PDB entry 8e58 contains 1 copy of Pfam domain PF16905 (Voltage-dependent L-type calcium channel, IQ-associated) in Voltage-dependent L-type calcium channel subunit alpha-1S. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002077
Domain description: Voltage-dependent calcium channel, alpha-1 subunit
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR005446
Domain description: Voltage-dependent calcium channel, L-type, alpha-1 subunit
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR005821
Domain description: Ion transport domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR027359
Domain description: Voltage-dependent channel domain superfamily
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR002035
Domain description: von Willebrand factor, type A
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
IPR005421
Domain description: Voltage-dependent calcium channel, gamma-1 subunit
Occurring in:
  1. Voltage-dependent calcium channel gamma-1 subunit
IPR008368
Domain description: Voltage-dependent calcium channel, gamma subunit
Occurring in:
  1. Voltage-dependent calcium channel gamma-1 subunit
IPR005450
Domain description: Voltage-dependent calcium channel, L-type, alpha-1S subunit
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR036465
Domain description: von Willebrand factor A-like domain superfamily
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
IPR014873
Domain description: Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR013680
Domain description: Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
IPR013608
Domain description: VWA N-terminal
Occurring in:
  1. Voltage-dependent calcium channel subunit alpha-2/delta-1
IPR004031
Domain description: PMP-22/EMP/MP20/Claudin
Occurring in:
  1. Voltage-dependent calcium channel gamma-1 subunit
IPR031688
Domain description: Voltage-gated calcium channel subunit alpha, C-terminal
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S
IPR031649
Domain description: Voltage-dependent L-type calcium channel, IQ-associated domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1S