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Structure of SARS-CoV-1 Orf3a in late endosome/lysosome-like environment, MSP1D1 nanodisc

Source organisms:
Biochemical function: lipid binding
Biological process: lipoprotein metabolic process
Cellular component: extracellular region

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF01442
Domain description: Apolipoprotein A1/A4/E domain
Occurring in:
  1. Truncated apolipoprotein A-I
The deposited structure of PDB entry 8eqs contains 2 copies of Pfam domain PF01442 (Apolipoprotein A1/A4/E domain) in Truncated apolipoprotein A-I. Showing 1 copy in chain C.

PF11289
Domain description: Betacoronavirus viroporin
Occurring in:
  1. ORF3a protein
The deposited structure of PDB entry 8eqs contains 2 copies of Pfam domain PF11289 (Betacoronavirus viroporin) in ORF3a protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR024407
Domain description: Protein 3a, betacoronavirus
Occurring in:
  1. ORF3a protein
IPR000074
Domain description: Apolipoprotein A/E
Occurring in:
  1. Truncated apolipoprotein A-I
IPR046446
Domain description: 3a-like viroporin, cytosolic domain, alpha/betacoronavirus
Occurring in:
  1. ORF3a protein
IPR046445
Domain description: 3a-like viroporin, transmembrane domain, alpha/betacoronavirus
Occurring in:
  1. ORF3a protein

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