› › Structure analysis

Structure of SARS-CoV-1 Orf3a in late endosome/lysosome-like environment, MSP1D1 nanodisc

Electron Microscopy
3.1Å resolution
PDB entry 8eqs coloured by chain, front view.
PDB entry 8eqs coloured by chain, side view.
PDB entry 8eqs coloured by chain, top view.
Source organisms:
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Truncated apolipoprotein A-I and ORF3a protein
hide full assembly name
Multimeric state: hetero tetramer
Accessible surface area: 22514.61 Å2
Buried surface area: 8911.42 Å2
Dissociation area: 1,164.88 Å2
Dissociation energy (ΔGdiss): 4.42 kcal/mol
Dissociation entropy (TΔSdiss): 19.44 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-135988

Macromolecules

ORF3a protein
Chains: A, B
Length: 330 amino acids
Theoretical weight: 36.27 KDa
Source organism: Severe acute respiratory syndrome coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: P59632 (Residues: 1-274; Coverage: 100%)
Gene name: 3a
Pfam: Betacoronavirus viroporin
InterPro:
ORF3a protein in PDB entry 8eqs, assembly 1, front view.
ORF3a protein in PDB entry 8eqs, assembly 1, side view.
ORF3a protein in PDB entry 8eqs, assembly 1, top view.
Molecule details ›

Search similar proteins

Truncated apolipoprotein A-I
Chains: C, D
Length: 211 amino acids
Theoretical weight: 24.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02647 (Residues: 79-267; Coverage: 76%)
Gene name: APOA1
Pfam: Apolipoprotein A1/A4/E domain
InterPro: Apolipoprotein A/E
Truncated apolipoprotein A-I in PDB entry 8eqs, assembly 1, front view.
Truncated apolipoprotein A-I in PDB entry 8eqs, assembly 1, side view.
Truncated apolipoprotein A-I in PDB entry 8eqs, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links