Function and Biology Details
Reactions catalysed:
(1a) S-adenosyl-L-methionine + G(5')pppAACA-[mRNA] = S-adenosyl-L-homocysteine + G(5')pppAmACA-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
(1a) (5')pppAACA-[mRNA] + (protein L)-L-histidine = diphosphate + (protein L)-L-histidyl-(5')phosphonato-AACA-[mRNA] + H(2)O
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
RNA-directed RNA polymerase L and Phosphoprotein (preferred)
PDBe Complex ID:
PDB-CPX-136999 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RNA-directed RNA polymerase L
Molecule details ›
Chain: A
Length: 1497 amino acids
Theoretical weight: 173.27 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 1497 amino acids
Theoretical weight: 173.27 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P28887 (Residues: 1-1460; Coverage: 67%)
Sequence domains:
Phosphoprotein
Molecule details ›
Chains: B, C, D, E
Length: 256 amino acids
Theoretical weight: 29.06 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Pneumovirus phosphoprotein
Length: 256 amino acids
Theoretical weight: 29.06 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P03421 (Residues: 1-241; Coverage: 100%)
Sequence domains: Pneumovirus phosphoprotein
