› › Structure analysis

Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1

Electron Microscopy
2.52Å resolution
PDB entry 8fpi coloured by chain, front view.
PDB entry 8fpi coloured by chain, side view.
PDB entry 8fpi coloured by chain, top view.
Source organism: Human respiratory syncytial virus A2
Assembly composition:
hetero pentamer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Phosphoprotein and RNA-directed RNA polymerase L
hide full assembly name
Multimeric state: hetero pentamer
Accessible surface area: 58238.49 Å2
Buried surface area: 17284.37 Å2
Dissociation area: 3,642.12 Å2
Dissociation energy (ΔGdiss): 35.35 kcal/mol
Dissociation entropy (TΔSdiss): 14.11 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136999

Macromolecules

RNA-directed RNA polymerase L
Chain: A
Length: 1497 amino acids
Theoretical weight: 173.27 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P28887 (Residues: 1-1460; Coverage: 67%)
Gene name: L
Pfam:
RNA-directed RNA polymerase L in PDB entry 8fpi, assembly 1, front view.
RNA-directed RNA polymerase L in PDB entry 8fpi, assembly 1, side view.
RNA-directed RNA polymerase L in PDB entry 8fpi, assembly 1, top view.
Molecule details ›

Search similar proteins

Phosphoprotein
Chains: B, C, D, E
Length: 256 amino acids
Theoretical weight: 29.06 KDa
Source organism: Human respiratory syncytial virus A2
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P03421 (Residues: 1-241; Coverage: 100%)
Gene name: P
Pfam: Pneumovirus phosphoprotein
Phosphoprotein in PDB entry 8fpi, assembly 1, front view.
Phosphoprotein in PDB entry 8fpi, assembly 1, side view.
Phosphoprotein in PDB entry 8fpi, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links