Assemblies
Multimeric state:
hetero octamer
Accessible surface area:
38872.36 Å2
Buried surface area:
14288.57 Å2
Dissociation area:
715.43
Å2
Dissociation energy (ΔGdiss):
-11.14
kcal/mol
Dissociation entropy (TΔSdiss):
13.47
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-240493
Macromolecules
Chain: 0
Length: 157 amino acids
Theoretical weight: 18.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Core binding factor beta subunit
Length: 157 amino acids
Theoretical weight: 18.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q13951 (Residues: 1-157; Coverage: 86%)
Pfam: Core binding factor beta subunit
Chain: 1
Length: 178 amino acids
Theoretical weight: 21.16 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
Pfam: Retroviral Vif (Viral infectivity) protein
Length: 178 amino acids
Theoretical weight: 21.16 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
- Canonical:
P12504 (Residues: 1-176; Coverage: 92%)
Pfam: Retroviral Vif (Viral infectivity) protein
Chain: A
Length: 189 amino acids
Theoretical weight: 22.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt: Gene name: APOBEC3H
Pfam: APOBEC3
Length: 189 amino acids
Theoretical weight: 22.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt: Gene name: APOBEC3H
Pfam: APOBEC3
Chain: x
Length: 314 amino acids
Theoretical weight: 36.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Cullin family
Length: 314 amino acids
Theoretical weight: 36.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q93034 (Residues: 11-320; Coverage: 40%)
Pfam: Cullin family
Chain: y
Length: 102 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Ubiquitin family
Length: 102 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15370 (Residues: 1-102; Coverage: 86%)
Pfam: Ubiquitin family
Chain: z
Length: 96 amino acids
Theoretical weight: 10.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Skp1 family, tetramerisation domain
Length: 96 amino acids
Theoretical weight: 10.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15369 (Residues: 17-112; Coverage: 86%)
Pfam: Skp1 family, tetramerisation domain
Name:
RNA(5'-R(AP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3')
Representative chains: B
Length: 10 nucleotides
Theoretical weight: 3.04 KDa
Representative chains: B
Length: 10 nucleotides
Theoretical weight: 3.04 KDa
Name:
RNA(5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Representative chains: C
Length: 9 nucleotides
Theoretical weight: 2.92 KDa
Representative chains: C
Length: 9 nucleotides
Theoretical weight: 2.92 KDa