Structure analysis

Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state

X-ray diffraction
2.35Å resolution
Source organism: Cavia porcellus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 18403.59 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-124710
Assembly 2
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Multimeric state: monomeric
Accessible surface area: 18464.33 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-124710

Macromolecules

Chains: A, B
Length: 423 amino acids
Theoretical weight: 45.96 KDa
Source organism: Cavia porcellus
Expression system: Escherichia coli
UniProt:
  • Canonical: H0VVB1 (Residues: 75-497; Coverage: 80%)
Gene name: KPNA2
Pfam:
InterPro:
PDBe-KB: UniProt Coverage View: H0VVB1  
142350100150200250300350400
 
100200300400
UniProt
H0VVB1
Chains
Domains
Secondary structure
Sequence conservation

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