Function and Biology Details
Reactions catalysed:
ATP + H(2)O = ADP + phosphate
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero 61-mer (preferred)
PDBe Complex ID:
PDB-CPX-293049 (preferred)
Entry contents:
42 distinct polypeptide molecules
5 distinct RNA molecules
5 distinct RNA molecules
Macromolecules (47 distinct):
U6 snRNA-associated Sm-like protein LSm2
Molecule details ›
Chain: 6a
Length: 95 amino acids
Theoretical weight: 10.85 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: LSM domain
Length: 95 amino acids
Theoretical weight: 10.85 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q9Y333 (Residues: 1-95; Coverage: 100%)
Sequence domains: LSM domain
U6 snRNA-associated Sm-like protein LSm3
Molecule details ›
Chain: 6b
Length: 102 amino acids
Theoretical weight: 11.86 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: LSM domain
Length: 102 amino acids
Theoretical weight: 11.86 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62310 (Residues: 1-102; Coverage: 100%)
Sequence domains: LSM domain
U6 snRNA-associated Sm-like protein LSm4
U6 snRNA-associated Sm-like protein LSm5
U6 snRNA-associated Sm-like protein LSm6
U6 snRNA-associated Sm-like protein LSm7
U6 snRNA-associated Sm-like protein LSm8
Pre-mRNA-processing-splicing factor 8
116 kDa U5 small nuclear ribonucleoprotein component
U5 small nuclear ribonucleoprotein 200 kDa helicase
U5 small nuclear ribonucleoprotein 40 kDa protein
Small nuclear ribonucleoprotein-associated proteins B and B'
Small nuclear ribonucleoprotein Sm D1
Small nuclear ribonucleoprotein Sm D2
Small nuclear ribonucleoprotein F
Small nuclear ribonucleoprotein E
Small nuclear ribonucleoprotein G
Small nuclear ribonucleoprotein Sm D3
U4/U6 small nuclear ribonucleoprotein Prp3
U4/U6 small nuclear ribonucleoprotein Prp4
U4/U6 small nuclear ribonucleoprotein Prp31
NHP2-like protein 1
Thioredoxin-like protein 4A
Pre-mRNA-processing factor 6
RNA-binding protein 42
U4/U6.U5 tri-snRNP-associated protein 1
Ubiquitin carboxyl-terminal hydrolase 39
Probable ATP-dependent RNA helicase DDX23
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
Serine/threonine-protein kinase PRP4 homolog
U2 small nuclear ribonucleoprotein A'
U2 small nuclear ribonucleoprotein B''
Splicing factor 3A subunit 1
Splicing factor 3A subunit 2
Splicing factor 3A subunit 3
Splicing factor 3B subunit 1
Splicing factor 3B subunit 2
Splicing factor 3B subunit 3
Splicing factor 3B subunit 4
Splicing factor 3B subunit 6
PHD finger-like domain-containing protein 5A
Splicing factor 3B subunit 5
