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crystal structure of yeast cytosine deaminase mutant yCD-RQ-1/8SAH in complex with (R)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: metal ion binding
Biological process: cytidine metabolic process
Cellular component: cytoplasm

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EC 3.5.4.1: Cytosine deaminase

Reaction catalysed:
Cytosine + H(2)O = uracil + NH(3)
Systematic name:
Cytosine aminohydrolase
Alternative Name(s):
  • Cytosine aminohydrolase
  • Isocytosine deaminase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00383
Domain description: Cytidine and deoxycytidylate deaminase zinc-binding region
Occurring in:
  1. Cytosine deaminase
The deposited structure of PDB entry 8i3p contains 2 copies of Pfam domain PF00383 (Cytidine and deoxycytidylate deaminase zinc-binding region) in Cytosine deaminase. Showing 1 copy in chain B.

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