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Crystal structure of Acyl-CoA dehydrogenase complexed with Acetyl-CoA from Thermobifida fusca

Source organism: Thermobifida fusca
Biochemical function: flavin adenine dinucleotide binding
Biological process: not assigned
Cellular component: not assigned

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EC 6.2.1.5: Succinate--CoA ligase (ADP-forming)

Reaction catalysed:
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
Systematic name:
Succinate:CoA ligase (ADP-forming)
Alternative Name(s):
  • A-SCS
  • A-STK (adenin nucleotide-linked succinate thiokinase)
  • STK
  • Succinate thiokinase
  • Succinic thiokinase
  • Succinyl coenzyme A synthetase
  • Succinyl coenzyme A synthetase (adenosine diphosphate-forming)
  • Succinyl-CoA synthetase
  • Succinyl-CoA synthetase (ADP-forming)

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF08028
Domain description: Acyl-CoA dehydrogenase, C-terminal domain
Occurring in:
  1. Succinate--CoA ligase [ADP-forming] subunit alpha

PF00441
Domain description: Acyl-CoA dehydrogenase, C-terminal domain
Occurring in:
  1. Succinate--CoA ligase [ADP-forming] subunit alpha
The deposited structure of PDB entry 8i4r contains 1 copy of Pfam domain PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) in Acyl-CoA dehydrogenase. Showing 1 copy in chain A.

PF02770
Domain description: Acyl-CoA dehydrogenase, middle domain
Occurring in:
  1. Succinate--CoA ligase [ADP-forming] subunit alpha
The deposited structure of PDB entry 8i4r contains 1 copy of Pfam domain PF02770 (Acyl-CoA dehydrogenase, middle domain) in Acyl-CoA dehydrogenase. Showing 1 copy in chain A.

PF02771
Domain description: Acyl-CoA dehydrogenase, N-terminal domain
Occurring in:
  1. Succinate--CoA ligase [ADP-forming] subunit alpha
The deposited structure of PDB entry 8i4r contains 1 copy of Pfam domain PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) in Acyl-CoA dehydrogenase. Showing 1 copy in chain A.

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