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Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound niacin

Source organism: Homo sapiens
Biochemical function: protein binding
Biological process: G protein-coupled receptor signaling pathway
Cellular component: plasma membrane

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 8j6l contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 7 copies in chain B.

PF00001
Domain description: 7 transmembrane receptor (rhodopsin family)
Occurring in:
  1. Hydroxycarboxylic acid receptor 2
The deposited structure of PDB entry 8j6l contains 1 copy of Pfam domain PF00001 (7 transmembrane receptor (rhodopsin family)) in Hydroxycarboxylic acid receptor 2. Showing 1 copy in chain E [auth R].

PF00631
Domain description: GGL domain
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
The deposited structure of PDB entry 8j6l contains 1 copy of Pfam domain PF00631 (GGL domain) in Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2. Showing 1 copy in chain C [auth G].

PF00503
Domain description: G-protein alpha subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(i) subunit alpha-1
The deposited structure of PDB entry 8j6l contains 1 copy of Pfam domain PF00503 (G-protein alpha subunit) in Guanine nucleotide-binding protein G(i) subunit alpha-1. Showing 1 copy in chain A.

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