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Bovine Xanthine Oxidoreductase Crystallized with oxypurinol

Source organism: Bos taurus
Biochemical function: FAD binding
Biological process: xanthine catabolic process
Cellular component: peroxisome

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EC 1.17.3.2: Xanthine oxidase

Reaction catalysed:
Xanthine + H(2)O + O(2) = urate + H(2)O(2)
Systematic name:
Xanthine:oxygen oxidoreductase
Alternative Name(s):
  • Hypoxanthine oxidase
  • Hypoxanthine-xanthine oxidase
  • Hypoxanthine:oxygen oxidoreductase
  • Schardinger enzyme
  • Xanthine oxidoreductase
  • Xanthine:O(2) oxidoreductase
  • Xanthine:xanthine oxidase

EC 1.17.1.4: Xanthine dehydrogenase

Reaction catalysed:
Xanthine + NAD(+) + H(2)O = urate + NADH
Systematic name:
Xanthine:NAD(+) oxidoreductase
Alternative Name(s):
  • NAD-xanthine dehydrogenase
  • Xanthine oxidoreductase
  • Xanthine-NAD oxidoreductase
  • Xanthine/NAD(+) oxidoreductase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF20256
Domain description: Molybdopterin cofactor-binding domain
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF20256 (Molybdopterin cofactor-binding domain) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

PF02738
Domain description: Molybdopterin cofactor-binding domain
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF02738 (Molybdopterin cofactor-binding domain) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

PF01315
Domain description: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF01315 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

PF03450
Domain description: CO dehydrogenase flavoprotein C-terminal domain
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF03450 (CO dehydrogenase flavoprotein C-terminal domain) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

PF00941
Domain description: FAD binding domain in molybdopterin dehydrogenase
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF00941 (FAD binding domain in molybdopterin dehydrogenase) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

PF01799
Domain description: [2Fe-2S] binding domain
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF01799 ([2Fe-2S] binding domain) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

PF00111
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. Xanthine dehydrogenase/oxidase
The deposited structure of PDB entry 8j79 contains 2 copies of Pfam domain PF00111 (2Fe-2S iron-sulfur cluster binding domain) in Xanthine dehydrogenase/oxidase. Showing 1 copy in chain B.

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