8jbg

Electron Microscopy
2.8Å resolution

Neurokinin B bound to active human neurokinin 3 receptor in complex with Gq

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-276190 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Neuromedin-K receptor Chain: B
Molecule details ›
Chain: B
Length: 1428 amino acids
Theoretical weight: 158.09 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: D
Molecule details ›
Chain: D
Length: 377 amino acids
Theoretical weight: 41.06 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
ScFv16 nanobody Chain: E
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: G
Neurokinin-B Chain: A
Guanine nucleotide-binding protein Gq (G324) Chain: C

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.8Å
Relevant EMDB volumes: EMD-36145
Expression systems:
  • Spodoptera frugiperda
  • Escherichia coli