› › Structure analysis

T1AM-bound mTAAR1-Gs protein complex

Electron Microscopy
3.1Å resolution
PDB entry 8jlj coloured by chain, front view.
PDB entry 8jlj coloured by chain, side view.
PDB entry 8jlj coloured by chain, top view.
Source organisms:
Assembly composition:
hetero pentamer (preferred)
Entry contents: 5 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero pentamer
Accessible surface area: 52820.52 Å2
Buried surface area: 10978.97 Å2
Dissociation area: 868.34 Å2
Dissociation energy (ΔGdiss): -4.5 kcal/mol
Dissociation entropy (TΔSdiss): 13.6 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-240820

Macromolecules

Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Chain: A
Length: 361 amino acids
Theoretical weight: 41.88 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P63096 (Residues: 1-19, 61-181, 229-242; Coverage: 41%)
  • Canonical: P63092 (Residues: 27-67, 205-251, 266-394; Coverage: 55%)
    • nullnull
Gene names: GNAI1, GNAS, GNAS1, GSP
Pfam: G-protein alpha subunit
mGs in PDB entry 8jlj, assembly 1, front view.
mGs in PDB entry 8jlj, assembly 1, side view.
mGs in PDB entry 8jlj, assembly 1, top view.
Molecule details ›

Search similar proteins

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Chain: B
Length: 358 amino acids
Theoretical weight: 39.42 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P62873 (Residues: 2-340; Coverage: 100%)
Gene name: GNB1
Pfam: WD domain, G-beta repeat
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 in PDB entry 8jlj, assembly 1, front view.
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 in PDB entry 8jlj, assembly 1, side view.
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 in PDB entry 8jlj, assembly 1, top view.
Molecule details ›

Search similar proteins

Soluble cytochrome b562; Trace amine-associated receptor 1
Chain: R
Length: 446 amino acids
Theoretical weight: 50.42 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0ABE7 (Residues: 23-128; Coverage: 100%)
  • Canonical: Q923Y8 (Residues: 1-332; Coverage: 100%)
    • nullnull
Gene names: Ta1, Taar1, Tar1, Trar1, cybC
Pfam:
Soluble cytochrome b562 in PDB entry 8jlj, assembly 1, front view.
Soluble cytochrome b562 in PDB entry 8jlj, assembly 1, side view.
Soluble cytochrome b562 in PDB entry 8jlj, assembly 1, top view.
Molecule details ›

Search similar proteins

ScFv16
Chain: S
Length: 251 amino acids
Theoretical weight: 26.71 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
ScFv16 in PDB entry 8jlj, assembly 1, front view.
ScFv16 in PDB entry 8jlj, assembly 1, side view.
ScFv16 in PDB entry 8jlj, assembly 1, top view.
Molecule details ›

Search similar proteins

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Chain: Y
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P59768 (Residues: 1-71; Coverage: 100%)
Gene name: GNG2
Pfam: GGL domain
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 in PDB entry 8jlj, assembly 1, front view.
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 in PDB entry 8jlj, assembly 1, side view.
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 in PDB entry 8jlj, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links