Structure analysis

Structure of procaryotic Ago

Electron Microscopy
2.6Å resolution
Source organism: Geobacter sulfurreducens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct DNA/RNA hybrid molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero tetramer
Accessible surface area: 34073.9 Å2
Buried surface area: 11467.36 Å2
Dissociation area: 2,659.35 Å2
Dissociation energy (ΔGdiss): 24.55 kcal/mol
Dissociation entropy (TΔSdiss): 14.14 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-246539

Macromolecules

Chain: A
Length: 473 amino acids
Theoretical weight: 53.33 KDa
Source organism: Geobacter sulfurreducens
Expression system: Expression vector pET-mod
UniProt:
  • Canonical: Q74DF5 (Residues: 1-473; Coverage: 100%)
Gene name: GSU1361

Search similar proteins

Chain: B
Length: 587 amino acids
Theoretical weight: 66.65 KDa
Source organism: Geobacter sulfurreducens
Expression system: Expression vector pET-mod
UniProt:
  • Canonical: Q74DF6 (Residues: 1-587; Coverage: 100%)
Gene name: GSU1360
Pfam: SIR2-like domain

Search similar proteins

Name: DNA (41-mer)
Representative chains: C
Length: 41 nucleotides
Theoretical weight: 12.53 KDa

Search similar DNA

Name: DNA/RNA (21-mer)
Representative chains: D
Length: 21 nucleotides
Theoretical weight: 6.68 KDa

Search similar DNA