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Structure of the human ATP synthase bound to bedaquiline (membrane domain)

Source organism: Homo sapiens
Biochemical function: proton transmembrane transporter activity
Biological process: proton motive force-driven ATP synthesis
Cellular component: proton-transporting ATP synthase complex, coupling factor F(o)

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00137
Domain description: ATP synthase subunit C
Occurring in:
  1. ATP synthase F(0) complex subunit C1, mitochondrial
The deposited structure of PDB entry 8khf contains 8 copies of Pfam domain PF00137 (ATP synthase subunit C) in ATP synthase F(0) complex subunit C1, mitochondrial. Showing 1 copy in chain A [auth 1].

PF05680
Domain description: ATP synthase E chain
Occurring in:
  1. ATP synthase subunit e, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF05680 (ATP synthase E chain) in ATP synthase subunit e, mitochondrial. Showing 1 copy in chain S [auth T].

PF04718
Domain description: Mitochondrial ATP synthase g subunit
Occurring in:
  1. ATP synthase subunit g, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF04718 (Mitochondrial ATP synthase g subunit) in ATP synthase subunit g, mitochondrial. Showing 1 copy in chain R [auth S].

PF10206
Domain description: Mitochondrial F1F0-ATP synthase, subunit f
Occurring in:
  1. ATP synthase subunit f, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF10206 (Mitochondrial F1F0-ATP synthase, subunit f) in ATP synthase subunit f, mitochondrial. Showing 1 copy in chain Q [auth R].

PF00895
Domain description: ATP synthase protein 8
Occurring in:
  1. ATP synthase protein 8
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF00895 (ATP synthase protein 8) in ATP synthase protein 8. Showing 1 copy in chain P [auth Q].

PF08039
Domain description: Mitochondrial proteolipid
Occurring in:
  1. ATP synthase subunit ATP5MJ, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF08039 (Mitochondrial proteolipid) in ATP synthase subunit ATP5MJ, mitochondrial. Showing 1 copy in chain O [auth P].

PF00119
Domain description: ATP synthase A chain
Occurring in:
  1. ATP synthase subunit a
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF00119 (ATP synthase A chain) in ATP synthase subunit a. Showing 1 copy in chain N.

PF05873
Domain description: ATP synthase D chain, mitochondrial (ATP5H)
Occurring in:
  1. ATP synthase subunit d, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF05873 (ATP synthase D chain, mitochondrial (ATP5H)) in ATP synthase subunit d, mitochondrial. Showing 1 copy in chain M.

PF05405
Domain description: Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
Occurring in:
  1. ATP synthase F(0) complex subunit B1, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF05405 (Mitochondrial ATP synthase B chain precursor (ATP-synt_B)) in ATP synthase F(0) complex subunit B1, mitochondrial. Showing 1 copy in chain L [auth K].

PF04627
Domain description: Mitochondrial ATP synthase epsilon chain
Occurring in:
  1. ATP synthase subunit epsilon, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF04627 (Mitochondrial ATP synthase epsilon chain) in ATP synthase subunit epsilon, mitochondrial. Showing 1 copy in chain K [auth I].

PF21335
Domain description: Metazoan delta subunit of F1F0-ATP synthase, C-terminal domain
Occurring in:
  1. ATP synthase subunit delta, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF21335 (Metazoan delta subunit of F1F0-ATP synthase, C-terminal domain) in ATP synthase subunit delta, mitochondrial. Showing 1 copy in chain J [auth H].

PF02823
Domain description: ATP synthase, Delta/Epsilon chain, beta-sandwich domain
Occurring in:
  1. ATP synthase subunit delta, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF02823 (ATP synthase, Delta/Epsilon chain, beta-sandwich domain) in ATP synthase subunit delta, mitochondrial. Showing 1 copy in chain J [auth H].

PF00231
Domain description: ATP synthase
Occurring in:
  1. ATP synthase subunit gamma, mitochondrial
The deposited structure of PDB entry 8khf contains 1 copy of Pfam domain PF00231 (ATP synthase) in ATP synthase subunit gamma, mitochondrial. Showing 1 copy in chain I [auth G].

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