› 8odu

Electron Microscopy
5Å resolution

Chaetomium thermophilum Get1/Get2 heterotetramer in complex with a Get3 dimer (amphipol)

Released:
DOI: 10.2210/pdb8odu/pdb
PDB entry 8odu coloured by chain, front view.
PDB entry 8odu coloured by chain, side view.
PDB entry 8odu coloured by chain, top view.
Source organism: Thermochaetoides thermophila DSM 1495
Primary publication:
The GET insertase exhibits conformational plasticity and induces membrane thinning.
McDowell MA, Heimes M, Enkavi G, Farkas Á, Saar D, Wild K, Schwappach B, Vattulainen I, Sinning I
Nat Commun 14 7355 (2023)
PMID: 37963916
Related structures: EMD-16817

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-236038 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Anion-transporting ATPase-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 334 amino acids
Theoretical weight: 37.13 KDa
Source organism: Thermochaetoides thermophila DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0SFE0 (Residues: 14-339; Coverage: 96%)
Gene name: CTHT_0061710
Sequence domains: Anion-transporting ATPase
Protein GET1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 409 amino acids
Theoretical weight: 45.57 KDa
Source organism: Thermochaetoides thermophila DSM 1495
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: G0RZE4 (Residues: 185-357; Coverage: 49%)
  • Canonical: G0S1H2 (Residues: 1-209; Coverage: 100%)
Gene names: CTHT_0002670, CTHT_0013590, GET1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5Å
Relevant EMDB volumes: EMD-16817
Expression systems:
  • Escherichia coli
  • Saccharomyces cerevisiae

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