Assemblies
Multimeric state:
hetero 53-mer
Accessible surface area:
753909.54 Å2
Buried surface area:
446049.09 Å2
Dissociation area:
1,402.68
Å2
Dissociation energy (ΔGdiss):
3.87
kcal/mol
Dissociation entropy (TΔSdiss):
16.08
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-240072
Macromolecules
Chain: 1
Length: 476 amino acids
Theoretical weight: 52.28 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 476 amino acids
Theoretical weight: 52.28 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P38377 (Residues: 1-476; Coverage: 100%)
Pfam:
Chain: 2
Length: 68 amino acids
Theoretical weight: 7.75 KDa
Source organism: Homo sapiens
UniProt:
Pfam: SecE/Sec61-gamma subunits of protein translocation complex
Length: 68 amino acids
Theoretical weight: 7.75 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P60059 (Residues: 1-68; Coverage: 100%)
Pfam: SecE/Sec61-gamma subunits of protein translocation complex
Chain: 3
Length: 96 amino acids
Theoretical weight: 9.99 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Sec61beta family
Length: 96 amino acids
Theoretical weight: 9.99 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P60468 (Residues: 1-96; Coverage: 100%)
Pfam: Sec61beta family
Chain: A
Length: 794 amino acids
Theoretical weight: 89.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam: E3 UFM1-protein ligase 1
Length: 794 amino acids
Theoretical weight: 89.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
O94874 (Residues: 1-794; Coverage: 100%)
Pfam: E3 UFM1-protein ligase 1
Chain: B
Length: 506 amino acids
Theoretical weight: 56.98 KDa
Source organism: Homo sapiens
UniProt:
Pfam: CDK5 regulatory subunit-associated protein 3
Length: 506 amino acids
Theoretical weight: 56.98 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q96JB5 (Residues: 1-506; Coverage: 100%)
Pfam: CDK5 regulatory subunit-associated protein 3
Chain: C
Length: 314 amino acids
Theoretical weight: 35.66 KDa
Source organism: Homo sapiens
UniProt:
Pfam: DDRGK domain
Length: 314 amino acids
Theoretical weight: 35.66 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q96HY6 (Residues: 1-314; Coverage: 100%)
Pfam: DDRGK domain
Chain: D
Length: 85 amino acids
Theoretical weight: 9.13 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ubiquitin fold modifier 1 protein
Length: 85 amino acids
Theoretical weight: 9.13 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61960 (Residues: 1-85; Coverage: 100%)
Pfam: Ubiquitin fold modifier 1 protein
Chain: K
Length: 245 amino acids
Theoretical weight: 26.62 KDa
Source organism: Homo sapiens
UniProt:
Pfam: eIF-6 family
Length: 245 amino acids
Theoretical weight: 26.62 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P56537 (Residues: 1-245; Coverage: 100%)
Pfam: eIF-6 family
Chain: LA
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62917 (Residues: 1-257; Coverage: 100%)
Pfam:
Chain: LB
Length: 403 amino acids
Theoretical weight: 46.21 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L3
Length: 403 amino acids
Theoretical weight: 46.21 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P39023 (Residues: 1-403; Coverage: 100%)
Pfam: Ribosomal protein L3
Chain: LC
Length: 427 amino acids
Theoretical weight: 47.8 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 427 amino acids
Theoretical weight: 47.8 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P36578 (Residues: 1-427; Coverage: 100%)
Pfam:
Chain: LD
Length: 297 amino acids
Theoretical weight: 34.43 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 297 amino acids
Theoretical weight: 34.43 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P46777 (Residues: 1-297; Coverage: 100%)
Pfam:
Chain: LE
Length: 288 amino acids
Theoretical weight: 32.81 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 288 amino acids
Theoretical weight: 32.81 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q02878 (Residues: 1-288; Coverage: 100%)
Pfam:
Chain: LF
Length: 248 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 248 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P18124 (Residues: 1-248; Coverage: 100%)
Pfam:
Chain: LG
Length: 266 amino acids
Theoretical weight: 30.06 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Length: 266 amino acids
Theoretical weight: 30.06 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62424 (Residues: 1-266; Coverage: 100%)
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Chain: LH
Length: 192 amino acids
Theoretical weight: 21.9 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L6
Length: 192 amino acids
Theoretical weight: 21.9 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P32969 (Residues: 1-192; Coverage: 100%)
Pfam: Ribosomal protein L6
Chain: LI
Length: 214 amino acids
Theoretical weight: 24.55 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L16p/L10e
Length: 214 amino acids
Theoretical weight: 24.55 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q96L21 (Residues: 1-214; Coverage: 100%)
Pfam: Ribosomal protein L16p/L10e
Chain: LJ
Length: 178 amino acids
Theoretical weight: 20.29 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 178 amino acids
Theoretical weight: 20.29 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62913 (Residues: 1-178; Coverage: 100%)
Pfam:
Chain: LL
Length: 211 amino acids
Theoretical weight: 24.32 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L13e
Length: 211 amino acids
Theoretical weight: 24.32 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P26373 (Residues: 1-211; Coverage: 100%)
Pfam: Ribosomal protein L13e
Chain: LM
Length: 215 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L14
Length: 215 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P50914 (Residues: 1-215; Coverage: 100%)
Pfam: Ribosomal protein L14
Chain: LN
Length: 204 amino acids
Theoretical weight: 24.21 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L15
Length: 204 amino acids
Theoretical weight: 24.21 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61313 (Residues: 1-204; Coverage: 100%)
Pfam: Ribosomal L15
Chain: LO
Length: 203 amino acids
Theoretical weight: 23.63 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L13
Length: 203 amino acids
Theoretical weight: 23.63 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P40429 (Residues: 1-203; Coverage: 100%)
Pfam: Ribosomal protein L13
Chain: LP
Length: 184 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L22p/L17e
Length: 184 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P18621 (Residues: 1-184; Coverage: 100%)
Pfam: Ribosomal protein L22p/L17e
Chain: LQ
Length: 188 amino acids
Theoretical weight: 21.69 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein 60S L18 and 50S L18e
Length: 188 amino acids
Theoretical weight: 21.69 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q07020 (Residues: 1-188; Coverage: 100%)
Pfam: Ribosomal protein 60S L18 and 50S L18e
Chain: LR
Length: 196 amino acids
Theoretical weight: 23.54 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L19e
Length: 196 amino acids
Theoretical weight: 23.54 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P84098 (Residues: 1-196; Coverage: 100%)
Pfam: Ribosomal protein L19e
Chain: LS
Length: 176 amino acids
Theoretical weight: 20.81 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Length: 176 amino acids
Theoretical weight: 20.81 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q02543 (Residues: 1-176; Coverage: 100%)
Pfam: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Chain: LT
Length: 160 amino acids
Theoretical weight: 18.61 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L21e
Length: 160 amino acids
Theoretical weight: 18.61 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P46778 (Residues: 1-160; Coverage: 100%)
Pfam: Ribosomal protein L21e
Chain: LU
Length: 128 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L22e protein family
Length: 128 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P35268 (Residues: 1-128; Coverage: 100%)
Pfam: Ribosomal L22e protein family
Chain: LV
Length: 140 amino acids
Theoretical weight: 14.89 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L14p/L23e
Length: 140 amino acids
Theoretical weight: 14.89 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62829 (Residues: 1-140; Coverage: 100%)
Pfam: Ribosomal protein L14p/L23e
Chain: LW
Length: 157 amino acids
Theoretical weight: 17.83 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L24e
Length: 157 amino acids
Theoretical weight: 17.83 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P83731 (Residues: 1-157; Coverage: 100%)
Pfam: Ribosomal protein L24e
Chain: LX
Length: 156 amino acids
Theoretical weight: 17.74 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 156 amino acids
Theoretical weight: 17.74 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62750 (Residues: 1-156; Coverage: 100%)
Pfam:
Chain: LY
Length: 145 amino acids
Theoretical weight: 17.3 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 145 amino acids
Theoretical weight: 17.3 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61254 (Residues: 1-145; Coverage: 100%)
Pfam:
Chain: LZ
Length: 136 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 136 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61353 (Residues: 1-136; Coverage: 100%)
Pfam:
Chain: La
Length: 148 amino acids
Theoretical weight: 16.6 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Length: 148 amino acids
Theoretical weight: 16.6 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P46776 (Residues: 1-148; Coverage: 100%)
Pfam: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Chain: Lb
Length: 159 amino acids
Theoretical weight: 17.8 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L29e protein family
Length: 159 amino acids
Theoretical weight: 17.8 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P47914 (Residues: 1-159; Coverage: 100%)
Pfam: Ribosomal L29e protein family
Chain: Lc
Length: 115 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Length: 115 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62888 (Residues: 1-115; Coverage: 100%)
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Chain: Ld
Length: 125 amino acids
Theoretical weight: 14.49 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L31e
Length: 125 amino acids
Theoretical weight: 14.49 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62899 (Residues: 1-125; Coverage: 100%)
Pfam: Ribosomal protein L31e
Chain: Le
Length: 135 amino acids
Theoretical weight: 15.9 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L32
Length: 135 amino acids
Theoretical weight: 15.9 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62910 (Residues: 1-135; Coverage: 100%)
Pfam: Ribosomal protein L32
Chain: Lf
Length: 110 amino acids
Theoretical weight: 12.56 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L35Ae
Length: 110 amino acids
Theoretical weight: 12.56 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P18077 (Residues: 1-110; Coverage: 100%)
Pfam: Ribosomal protein L35Ae
Chain: Lg
Length: 117 amino acids
Theoretical weight: 13.33 KDa
Source organism: Homo sapiens environmental sample
UniProt:
Pfam: Ribosomal protein L34e
Length: 117 amino acids
Theoretical weight: 13.33 KDa
Source organism: Homo sapiens environmental sample
UniProt:
- Canonical:
A0A6J3FY29 (Residues: 1-117; Coverage: 100%)
Pfam: Ribosomal protein L34e
Chain: Lh
Length: 123 amino acids
Theoretical weight: 14.59 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L29 protein
Length: 123 amino acids
Theoretical weight: 14.59 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P42766 (Residues: 1-123; Coverage: 100%)
Pfam: Ribosomal L29 protein
Chain: Li
Length: 105 amino acids
Theoretical weight: 12.29 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L36e
Length: 105 amino acids
Theoretical weight: 12.29 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
Q9Y3U8 (Residues: 1-105; Coverage: 100%)
Pfam: Ribosomal protein L36e
Chain: Lj
Length: 97 amino acids
Theoretical weight: 11.11 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L37e
Length: 97 amino acids
Theoretical weight: 11.11 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61927 (Residues: 1-97; Coverage: 100%)
Pfam: Ribosomal protein L37e
Chain: Lk
Length: 70 amino acids
Theoretical weight: 8.24 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L38e protein family
Length: 70 amino acids
Theoretical weight: 8.24 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P63173 (Residues: 1-70; Coverage: 100%)
Pfam: Ribosomal L38e protein family
Chain: Ll
Length: 51 amino acids
Theoretical weight: 6.43 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L39 protein
Length: 51 amino acids
Theoretical weight: 6.43 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62891 (Residues: 1-51; Coverage: 100%)
Pfam: Ribosomal L39 protein
Chain: Lm
Length: 128 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 128 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62987 (Residues: 1-128; Coverage: 100%)
Pfam:
Chain: Lo
Length: 106 amino acids
Theoretical weight: 12.48 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L44
Length: 106 amino acids
Theoretical weight: 12.48 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P83881 (Residues: 1-106; Coverage: 100%)
Pfam: Ribosomal protein L44
Chain: Lp
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L37ae protein family
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P61513 (Residues: 1-92; Coverage: 100%)
Pfam: Ribosomal L37ae protein family
Chain: Lr
Length: 137 amino acids
Theoretical weight: 15.78 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal L28e protein family
Length: 137 amino acids
Theoretical weight: 15.78 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P46779 (Residues: 1-137; Coverage: 100%)
Pfam: Ribosomal L28e protein family
Chain: Lz
Length: 217 amino acids
Theoretical weight: 24.88 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L1p/L10e family
Length: 217 amino acids
Theoretical weight: 24.88 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P62906 (Residues: 1-217; Coverage: 100%)
Pfam: Ribosomal protein L1p/L10e family
Name:
28S ribosomal RNA
Representative chains: 5
Length: 5070 nucleotides
Theoretical weight: 1640.17 KDa
Rfam: Eukaryotic large subunit ribosomal RNA
Representative chains: 5
Length: 5070 nucleotides
Theoretical weight: 1640.17 KDa
Rfam: Eukaryotic large subunit ribosomal RNA
Name:
5S ribosomal RNA
Representative chains: 7
Length: 121 nucleotides
Theoretical weight: 39 KDa
Rfam: 5S ribosomal RNA
Representative chains: 7
Length: 121 nucleotides
Theoretical weight: 39 KDa
Rfam: 5S ribosomal RNA
Name:
5.8S ribosomal RNA
Representative chains: 8
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
Rfam: 5.8S ribosomal RNA
Representative chains: 8
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
Rfam: 5.8S ribosomal RNA