› › Structure analysis

Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Trehalose (Fragment-B-TRE)

X-ray diffraction
2.9Å resolution
PDB entry 8opx coloured by chain, front view.
PDB entry 8opx coloured by chain, side view.
PDB entry 8opx coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Probable fatty oxidation protein FadB and Putative acyltransferase Rv0859
hide full assembly name
Multimeric state: hetero tetramer
Accessible surface area: 82591.23 Å2
Buried surface area: 16504.92 Å2
Dissociation area: 3,860.56 Å2
Dissociation energy (ΔGdiss): 31.67 kcal/mol
Dissociation entropy (TΔSdiss): 17.3 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-129474

Macromolecules

Probable fatty oxidation protein FadB
Chains: A, B
Length: 736 amino acids
Theoretical weight: 78.01 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O53872 (Residues: 1-720; Coverage: 100%)
Gene names: Rv0860, fadB
Pfam:
Probable fatty oxidation protein FadB in PDB entry 8opx, assembly 1, front view.
Probable fatty oxidation protein FadB in PDB entry 8opx, assembly 1, side view.
Probable fatty oxidation protein FadB in PDB entry 8opx, assembly 1, top view.
Molecule details ›

Search similar proteins

Putative acyltransferase Rv0859
Chains: C, D
Length: 403 amino acids
Theoretical weight: 42.46 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O53871 (Residues: 1-403; Coverage: 100%)
Gene names: Rv0859, fadA
Pfam:
Putative acyltransferase Rv0859 in PDB entry 8opx, assembly 1, front view.
Putative acyltransferase Rv0859 in PDB entry 8opx, assembly 1, side view.
Putative acyltransferase Rv0859 in PDB entry 8opx, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links