Function and Biology

Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3

Source organism: Rattus norvegicus
Biochemical function: ionotropic glutamate receptor binding
Biological process: regulation of AMPA receptor activity
Cellular component: membrane

Sequence families

Pfam Protein families (Pfam)
PF00822
Domain description: PMP-22/EMP/MP20/Claudin family
Occurring in:
  1. Voltage-dependent calcium channel gamma-2 subunit
The deposited structure of PDB entry 8p3q contains 4 copies of Pfam domain PF00822 (PMP-22/EMP/MP20/Claudin family) in Voltage-dependent calcium channel gamma-2 subunit. Showing 1 copy in chain F.

PF00060
Domain description: Ligand-gated ion channel
Occurring in:
  1. Glutamate receptor 2
The deposited structure of PDB entry 8p3q contains 4 copies of Pfam domain PF00060 (Ligand-gated ion channel) in Glutamate receptor 2. Showing 1 copy in chain A.

PF10613
Domain description: Ligated ion channel L-glutamate- and glycine-binding site
Occurring in:
  1. Glutamate receptor 2
The deposited structure of PDB entry 8p3q contains 4 copies of Pfam domain PF10613 (Ligated ion channel L-glutamate- and glycine-binding site) in Glutamate receptor 2. Showing 1 copy in chain A.

PF01094
Domain description: Receptor family ligand binding region
Occurring in:
  1. Glutamate receptor 2
The deposited structure of PDB entry 8p3q contains 4 copies of Pfam domain PF01094 (Receptor family ligand binding region) in Glutamate receptor 2. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).