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8pem Overview
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8pem</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 8pem coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8pem</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 8pem coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8pem</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 8pem coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8pem</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_assembly_1_chain_front_image-800x800.png "Monomeric assembly 1 of PDB entry 8pem coloured by chain, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8pem</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_assembly_1_chain_side_image-800x800.png "Monomeric assembly 1 of PDB entry 8pem coloured by chain, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8pem</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_assembly_1_chain_top_image-800x800.png "Monomeric assembly 1 of PDB entry 8pem coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8pem</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_deposited_chain_front_image-800x800.png "PDB entry 8pem coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8pem</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_deposited_chain_side_image-800x800.png "PDB entry 8pem coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8pem</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_deposited_chain_top_image-800x800.png "PDB entry 8pem coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8pem</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 8pem coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8pem</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 8pem coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8pem</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>RNA-directed RNA polymerase NS5</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>S-ADENOSYL-L-HOMOCYSTEINE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8pem_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 8pem coloured by chemically distinct molecules, top view.")