› 8pmx

X-ray diffraction
3.92Å resolution

rat HEV P domain in complex with glycan-sensitive nAb p60.12

Released:
DOI: 10.2210/pdb8pmx/pdb
PDB entry 8pmx coloured by chain, front view.
PDB entry 8pmx coloured by chain, side view.
PDB entry 8pmx coloured by chain, top view.
Source organisms:
Entry authors: Ssebyatika G, Krey T

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246867 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Pro-secreted protein ORF2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 165 amino acids
Theoretical weight: 17.98 KDa
Source organism: Hepatitis E virus rat/R63/DEU/2009
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: E0XL23 (Residues: 445-603; Coverage: 25%)
Sequence domains: Structural protein 2 C-terminal domain
Fab p60.12-HC Chain: H
Molecule details ›
Chain: H
Length: 233 amino acids
Theoretical weight: 24.86 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
Fab p60.12-LC Chain: L
Molecule details ›
Chain: L
Length: 217 amino acids
Theoretical weight: 22.9 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P43212
Unit cell:
a: 112.856Å b: 112.856Å c: 184.439Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.304 0.3 0.362
Expression system: Drosophila melanogaster

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