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Cytoplasmic dynein-1 motor domain bound to dynactin-p150glued and LIS1

Source organisms:
Biochemical function: protein binding
Biological process: cell division
Cellular component: microtubule

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Platelet-activating factor acetylhydrolase IB subunit beta
  2. Cytoplasmic dynein 1 intermediate chain 2
The deposited structure of PDB entry 8pqw contains 28 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Platelet-activating factor acetylhydrolase IB subunit beta. Showing 7 copies in chain B.
The deposited structure of PDB entry 8pqw contains 2 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Cytoplasmic dynein 1 intermediate chain 2. Showing 1 copy in chain H (this domain is out of the observed residue ranges!).

PF08513
Domain description: LisH
Occurring in:
  1. Platelet-activating factor acetylhydrolase IB subunit beta
The deposited structure of PDB entry 8pqw contains 4 copies of Pfam domain PF08513 (LisH) in Platelet-activating factor acetylhydrolase IB subunit beta. Showing 1 copy in chain B (this domain is out of the observed residue ranges!).

PF11540
Domain description: Cytoplasmic dynein 1 intermediate chain 2
Occurring in:
  1. Cytoplasmic dynein 1 intermediate chain 2
The deposited structure of PDB entry 8pqw contains 2 copies of Pfam domain PF11540 (Cytoplasmic dynein 1 intermediate chain 2) in Cytoplasmic dynein 1 intermediate chain 2. Showing 1 copy in chain H (this domain is out of the observed residue ranges!).

PF12455
Domain description: Dynein associated protein
Occurring in:
  1. Dynactin subunit 1
The deposited structure of PDB entry 8pqw contains 2 copies of Pfam domain PF12455 (Dynein associated protein ) in Dynactin subunit 1. Showing 1 copy in chain F.

PF01302
Domain description: CAP-Gly domain
Occurring in:
  1. Dynactin subunit 1
The deposited structure of PDB entry 8pqw contains 2 copies of Pfam domain PF01302 (CAP-Gly domain) in Dynactin subunit 1. Showing 1 copy in chain F (this domain is out of the observed residue ranges!).

PF18199
Domain description: Dynein heavy chain C-terminal domain
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF18199 (Dynein heavy chain C-terminal domain) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF18198
Domain description: Dynein heavy chain AAA lid domain
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF18198 (Dynein heavy chain AAA lid domain) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF03028
Domain description: Dynein heavy chain region D6 P-loop domain
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF03028 (Dynein heavy chain region D6 P-loop domain ) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF12781
Domain description: ATP-binding dynein motor region
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF12781 (ATP-binding dynein motor region) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF12777
Domain description: Microtubule-binding stalk of dynein motor
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF12777 (Microtubule-binding stalk of dynein motor) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF12780
Domain description: P-loop containing dynein motor region D4
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF12780 (P-loop containing dynein motor region D4) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF22597
Domain description: Dynein heavy chain, ATPase lid domain
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1

PF12775
Domain description: P-loop containing dynein motor region
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF12775 (P-loop containing dynein motor region) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF17852
Domain description: Dynein heavy chain AAA lid domain
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF17852 (Dynein heavy chain AAA lid domain) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF12774
Domain description: Hydrolytic ATP binding site of dynein motor region
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF12774 (Hydrolytic ATP binding site of dynein motor region) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF08393
Domain description: Dynein heavy chain, N-terminal region 2
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF08393 (Dynein heavy chain, N-terminal region 2) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A.

PF08385
Domain description: Dynein heavy chain, N-terminal region 1
Occurring in:
  1. Cytoplasmic dynein 1 heavy chain 1
The deposited structure of PDB entry 8pqw contains 1 copy of Pfam domain PF08385 (Dynein heavy chain, N-terminal region 1) in Cytoplasmic dynein 1 heavy chain 1. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

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