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Human NDPK-C in complex with ADP

X-ray diffraction
1.255Å resolution
PDB entry 8qw3 coloured by chain, front view.
PDB entry 8qw3 coloured by chain, side view.
PDB entry 8qw3 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo hexamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Nucleoside diphosphate kinase 3
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Multimeric state: homo hexamer
Accessible surface area: 33091.94 Å2
Buried surface area: 22715.13 Å2
Dissociation area: 8,932.75 Å2
Dissociation energy (ΔGdiss): 54.47 kcal/mol
Dissociation entropy (TΔSdiss): 64.49 kcal/mol
Symmetry number: 6
PDBe Complex ID: PDB-CPX-171611

Macromolecules

Nucleoside diphosphate kinase 3
Chains: A, B, C, D, E, F
Length: 155 amino acids
Theoretical weight: 17.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13232 (Residues: 18-169; Coverage: 90%)
Gene name: NME3
Pfam: Nucleoside diphosphate kinase
Nucleoside diphosphate kinase 3 in PDB entry 8qw3, assembly 1, front view.
Nucleoside diphosphate kinase 3 in PDB entry 8qw3, assembly 1, side view.
Nucleoside diphosphate kinase 3 in PDB entry 8qw3, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q13232  
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