Assemblies
Assembly Name:
Complex I, NADH-ubiquinone oxidoreductase
Multimeric state:
hetero 45-mer
Accessible surface area:
255710.8 Å2
Buried surface area:
309521.28 Å2
Dissociation area:
697.96
Å2
Dissociation energy (ΔGdiss):
-2.85
kcal/mol
Dissociation entropy (TΔSdiss):
11.74
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-124487
Macromolecules
Chain: 6
Length: 224 amino acids
Theoretical weight: 24.72 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH ubiquinone oxidoreductase, 20 Kd subunit
Length: 224 amino acids
Theoretical weight: 24.72 KDa
Source organism: Mus musculus
UniProt:
- Canonical:
Q9DC70 (Residues: 1-224; Coverage: 100%)
Pfam: NADH ubiquinone oxidoreductase, 20 Kd subunit
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_1_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_1_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_1_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial</span>. Top view.")
Chain: C
Length: 263 amino acids
Theoretical weight: 30.19 KDa
Source organism: Mus musculus
UniProt:
Pfam: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
Length: 263 amino acids
Theoretical weight: 30.19 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9DCT2 (Residues: 1-263; Coverage: 100%)
Pfam: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_2_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_2_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_2_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial</span>. Top view.")
Chain: D
Length: 463 amino acids
Theoretical weight: 52.72 KDa
Source organism: Mus musculus
UniProt:
Pfam: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
Length: 463 amino acids
Theoretical weight: 52.72 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q91WD5 (Residues: 1-463; Coverage: 100%)
Pfam: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_3_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_3_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_3_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial</span>. Top view.")
Chain: 2
Length: 248 amino acids
Theoretical weight: 27.32 KDa
Source organism: Mus musculus
UniProt:
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
Length: 248 amino acids
Theoretical weight: 27.32 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9D6J6 (Residues: 1-248; Coverage: 100%)
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
![NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_4_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_4_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_4_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial</span>. Top view.")
Chain: 1
Length: 464 amino acids
Theoretical weight: 50.9 KDa
Source organism: Mus musculus
UniProt:
Pfam:
Length: 464 amino acids
Theoretical weight: 50.9 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q91YT0 (Residues: 1-464; Coverage: 100%)
Pfam:
![NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_5_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_5_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_5_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</span>. Top view.")
Chain: 3
Length: 727 amino acids
Theoretical weight: 79.87 KDa
Source organism: Mus musculus
UniProt:
Pfam:
Length: 727 amino acids
Theoretical weight: 79.87 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q91VD9 (Residues: 1-727; Coverage: 100%)
Pfam:
- 2Fe-2S iron-sulfur cluster binding domain
- NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
- NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain
- NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain
- Molybdopterin oxidoreductase
- NADH-ubiquinone oxidoreductase subunit G, C-terminal
Chain: 9
Length: 212 amino acids
Theoretical weight: 24.07 KDa
Source organism: Mus musculus
UniProt:
Pfam: 4Fe-4S dicluster domain
Length: 212 amino acids
Theoretical weight: 24.07 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q8K3J1 (Residues: 1-212; Coverage: 100%)
Pfam: 4Fe-4S dicluster domain
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_7_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_7_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_7_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial</span>. Top view.")
Chain: P
Length: 377 amino acids
Theoretical weight: 42.59 KDa
Source organism: Mus musculus
UniProt:
Pfam: NmrA-like family
Length: 377 amino acids
Theoretical weight: 42.59 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9DC69 (Residues: 1-377; Coverage: 100%)
Pfam: NmrA-like family
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_8_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_8_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_8_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial</span>. Top view.")
Chain: Q
Length: 175 amino acids
Theoretical weight: 19.81 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
Length: 175 amino acids
Theoretical weight: 19.81 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CXZ1 (Residues: 1-175; Coverage: 100%)
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_9_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_9_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_9_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial</span>. Top view.")
Chain: 7
Length: 116 amino acids
Theoretical weight: 13.04 KDa
Source organism: Mus musculus
UniProt:
Pfam: Zinc-finger domain
Length: 116 amino acids
Theoretical weight: 13.04 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P52503 (Residues: 1-116; Coverage: 100%)
Pfam: Zinc-finger domain
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_10_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_10_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_10_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial</span>. Top view.")
Chain: S
Length: 99 amino acids
Theoretical weight: 10.93 KDa
Source organism: Mus musculus
UniProt:
Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Length: 99 amino acids
Theoretical weight: 10.93 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQ75 (Residues: 1-99; Coverage: 100%)
Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_11_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_11_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_11_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2</span>. Top view.")
Chains: T, U
Length: 156 amino acids
Theoretical weight: 17.39 KDa
Source organism: Mus musculus
UniProt:
Pfam: Phosphopantetheine attachment site
Length: 156 amino acids
Theoretical weight: 17.39 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CR21 (Residues: 1-156; Coverage: 100%)
Pfam: Phosphopantetheine attachment site
Chain: V
Length: 116 amino acids
Theoretical weight: 13.38 KDa
Source organism: Mus musculus
UniProt:
Pfam: ETC complex I subunit conserved region
Length: 116 amino acids
Theoretical weight: 13.38 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CPP6 (Residues: 1-116; Coverage: 100%)
Pfam: ETC complex I subunit conserved region
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_13_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_13_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_13_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5</span>. Top view.")
Chain: W
Length: 131 amino acids
Theoretical weight: 15.31 KDa
Source organism: Mus musculus
UniProt:
Pfam: Complex1_LYR-like
Length: 131 amino acids
Theoretical weight: 15.31 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQZ5 (Residues: 1-131; Coverage: 100%)
Pfam: Complex1_LYR-like
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_14_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_14_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_14_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6</span>. Top view.")
Chain: q
Length: 145 amino acids
Theoretical weight: 17.11 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH ubiquinone oxidoreductase subunit NDUFA12
Length: 145 amino acids
Theoretical weight: 17.11 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q7TMF3 (Residues: 1-145; Coverage: 100%)
Pfam: NADH ubiquinone oxidoreductase subunit NDUFA12
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_15_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_15_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_15_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12</span>. Top view.")
Chain: r
Length: 113 amino acids
Theoretical weight: 12.64 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
Length: 113 amino acids
Theoretical weight: 12.64 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9Z1P6 (Residues: 1-113; Coverage: 100%)
Pfam: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_16_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_16_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_16_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7</span>. Top view.")
Chain: s
Length: 104 amino acids
Theoretical weight: 11.83 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Length: 104 amino acids
Theoretical weight: 11.83 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q8BK30 (Residues: 1-104; Coverage: 100%)
Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
![NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_17_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_17_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_17_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial</span>. Top view.")
Chain: A
Length: 115 amino acids
Theoretical weight: 13.25 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
Length: 115 amino acids
Theoretical weight: 13.25 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03899 (Residues: 1-115; Coverage: 100%)
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
Chain: H
Length: 318 amino acids
Theoretical weight: 36.11 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH dehydrogenase
Length: 318 amino acids
Theoretical weight: 36.11 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03888 (Residues: 1-318; Coverage: 100%)
Pfam: NADH dehydrogenase
Chain: J
Length: 172 amino acids
Theoretical weight: 18.66 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
Length: 172 amino acids
Theoretical weight: 18.66 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03925 (Residues: 1-172; Coverage: 100%)
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
Chain: K
Length: 98 amino acids
Theoretical weight: 10.64 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
Length: 98 amino acids
Theoretical weight: 10.64 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03903 (Residues: 1-98; Coverage: 100%)
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
Chain: L
Length: 607 amino acids
Theoretical weight: 68.55 KDa
Source organism: Mus musculus
UniProt:
Pfam:
Length: 607 amino acids
Theoretical weight: 68.55 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03921 (Residues: 1-607; Coverage: 100%)
Pfam:
Chain: M
Length: 459 amino acids
Theoretical weight: 51.94 KDa
Source organism: Mus musculus
UniProt:
Pfam:
Length: 459 amino acids
Theoretical weight: 51.94 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03911 (Residues: 1-459; Coverage: 100%)
Pfam:
Chain: N
Length: 345 amino acids
Theoretical weight: 38.8 KDa
Source organism: Mus musculus
UniProt:
Pfam:
Length: 345 amino acids
Theoretical weight: 38.8 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P03893 (Residues: 1-345; Coverage: 100%)
Pfam:
Chain: O
Length: 355 amino acids
Theoretical weight: 40.66 KDa
Source organism: Mus musculus
UniProt:
Pfam: Deoxynucleoside kinase
Length: 355 amino acids
Theoretical weight: 40.66 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q99LC3 (Residues: 1-355; Coverage: 100%)
Pfam: Deoxynucleoside kinase
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_25_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_25_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_25_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial</span>. Top view.")
Chain: X
Length: 172 amino acids
Theoretical weight: 20.03 KDa
Source organism: Mus musculus
UniProt:
Pfam: CHCH domain
Length: 172 amino acids
Theoretical weight: 20.03 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9DCJ5 (Residues: 1-172; Coverage: 100%)
Pfam: CHCH domain
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_26_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_26_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_26_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8</span>. Top view.")
Chain: Y
Length: 141 amino acids
Theoretical weight: 14.93 KDa
Source organism: Mus musculus
UniProt:
Pfam: Tim17/Tim22/Tim23/Pmp24 family
Length: 141 amino acids
Theoretical weight: 14.93 KDa
Source organism: Mus musculus
UniProt:
- Canonical: G5E814 (Residues: 3-143; Coverage: 99%)
Pfam: Tim17/Tim22/Tim23/Pmp24 family
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_27_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_27_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_27_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11</span>. Top view.")
Chain: Z
Length: 144 amino acids
Theoretical weight: 16.88 KDa
Source organism: Mus musculus
UniProt:
Pfam: GRIM-19 protein
Length: 144 amino acids
Theoretical weight: 16.88 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9ERS2 (Residues: 1-144; Coverage: 100%)
Pfam: GRIM-19 protein
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_28_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_28_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_28_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</span>. Top view.")
Chain: a
Length: 70 amino acids
Theoretical weight: 8.15 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase MWFE subunit
Length: 70 amino acids
Theoretical weight: 8.15 KDa
Source organism: Mus musculus
UniProt:
- Canonical: O35683 (Residues: 1-70; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase MWFE subunit
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_29_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_29_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_29_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</span>. Top view.")
Chain: b
Length: 84 amino acids
Theoretical weight: 9.38 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH dehydrogenase 1 alpha subcomplex subunit 3
Length: 84 amino acids
Theoretical weight: 9.38 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQ91 (Residues: 1-84; Coverage: 100%)
Pfam: NADH dehydrogenase 1 alpha subcomplex subunit 3
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_30_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_30_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_30_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3</span>. Top view.")
Chain: c
Length: 76 amino acids
Theoretical weight: 8.64 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Length: 76 amino acids
Theoretical weight: 8.64 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQY9 (Residues: 1-76; Coverage: 100%)
Pfam: NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
![NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_31_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_31_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_31_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial</span>. Top view.")
Chain: d
Length: 120 amino acids
Theoretical weight: 14.19 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)
Length: 120 amino acids
Theoretical weight: 14.19 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQ54 (Residues: 1-120; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)
![NADH dehydrogenase [ubiquinone] 1 subunit C2 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_32_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 subunit C2</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 subunit C2 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_32_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 subunit C2</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 subunit C2 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_32_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 subunit C2</span>. Top view.")
Chain: e
Length: 106 amino acids
Theoretical weight: 12.68 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
Length: 106 amino acids
Theoretical weight: 12.68 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q99LY9 (Residues: 1-106; Coverage: 100%)
Pfam: NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_33_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</span>. Front view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_33_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</span>. Side view.")
![NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_33_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</span>. Top view.")
Chain: f
Length: 57 amino acids
Theoretical weight: 6.97 KDa
Source organism: Mus musculus
UniProt:
Pfam: MNLL subunit
Length: 57 amino acids
Theoretical weight: 6.97 KDa
Source organism: Mus musculus
UniProt:
- Canonical: P0DN34 (Residues: 1-57; Coverage: 100%)
Pfam: MNLL subunit
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_34_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_34_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_34_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1</span>. Top view.")
Chain: g
Length: 151 amino acids
Theoretical weight: 17.46 KDa
Source organism: Mus musculus
UniProt:
Pfam: ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
Length: 151 amino acids
Theoretical weight: 17.46 KDa
Source organism: Mus musculus
UniProt:
- Canonical: O09111 (Residues: 1-151; Coverage: 100%)
Pfam: ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_35_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_35_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_35_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</span>. Top view.")
Chain: h
Length: 189 amino acids
Theoretical weight: 21.74 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
Length: 189 amino acids
Theoretical weight: 21.74 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQH3 (Residues: 1-189; Coverage: 100%)
Pfam: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_36_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_36_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_36_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial</span>. Top view.")
Chain: i
Length: 128 amino acids
Theoretical weight: 15.58 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
Length: 128 amino acids
Theoretical weight: 15.58 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q3UIU2 (Residues: 1-128; Coverage: 100%)
Pfam: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_37_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_37_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_37_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6</span>. Top view.")
Chain: j
Length: 105 amino acids
Theoretical weight: 11.98 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH dehydrogenase 1 beta subcomplex subunit 2
Length: 105 amino acids
Theoretical weight: 11.98 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CPU2 (Residues: 1-105; Coverage: 100%)
Pfam: NADH dehydrogenase 1 beta subcomplex subunit 2
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_38_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_38_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_38_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial</span>. Top view.")
Chain: k
Length: 104 amino acids
Theoretical weight: 11.71 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase B12 subunit family
Length: 104 amino acids
Theoretical weight: 11.71 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQZ6 (Residues: 1-104; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase B12 subunit family
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_39_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_39_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_39_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3</span>. Top view.")
Chain: l
Length: 186 amino acids
Theoretical weight: 21.9 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
Length: 186 amino acids
Theoretical weight: 21.9 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9D6J5 (Residues: 1-186; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_40_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_40_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_40_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial</span>. Top view.")
Chain: m
Length: 129 amino acids
Theoretical weight: 15.11 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
Length: 129 amino acids
Theoretical weight: 15.11 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQC7 (Residues: 1-129; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_41_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_41_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_41_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4</span>. Top view.")
Chain: n
Length: 179 amino acids
Theoretical weight: 22.02 KDa
Source organism: Mus musculus
UniProt:
Pfam: Complex 1 protein (LYR family)
Length: 179 amino acids
Theoretical weight: 22.02 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CQJ8 (Residues: 1-179; Coverage: 100%)
Pfam: Complex 1 protein (LYR family)
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_42_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_42_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_42_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</span>. Top view.")
Chain: o
Length: 137 amino acids
Theoretical weight: 16.36 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
Length: 137 amino acids
Theoretical weight: 16.36 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9CR61 (Residues: 1-137; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_43_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_43_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_43_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</span>. Top view.")
Chain: p
Length: 176 amino acids
Theoretical weight: 21.05 KDa
Source organism: Mus musculus
UniProt:
Pfam: NADH-ubiquinone oxidoreductase subunit 10
Length: 176 amino acids
Theoretical weight: 21.05 KDa
Source organism: Mus musculus
UniProt:
- Canonical: Q9DCS9 (Residues: 1-176; Coverage: 100%)
Pfam: NADH-ubiquinone oxidoreductase subunit 10
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 in PDB entry 8rgq, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_44_front_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10</span>. Front view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 in PDB entry 8rgq, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_44_side_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10</span>. Side view.")
![NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 in PDB entry 8rgq, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8rgq_entity_44_top_image-200x200.png "Hetero 45-meric assembly 1 of PDB entry <span class='highlight'>8rgq</span> contains 1 copy of <span class='highlight'>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10</span>. Top view.")