› › Structure analysis

Crystal structure of the JIP1-JIP2-SH3 heterodimer and the JIP2-JIP2-SH3 homodimer

X-ray diffraction
1.867Å resolution
PDB entry 8rpp coloured by chain, front view.
PDB entry 8rpp coloured by chain, side view.
PDB entry 8rpp coloured by chain, top view.
Source organism: Homo sapiens
Assemblies composition:
hetero dimer (preferred)
homo dimer
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: C-Jun-amino-terminal kinase-interacting protein 1 and C-Jun-amino-terminal kinase-interacting protein 2
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 6139.65 Å2
Buried surface area: 1764.4 Å2
Dissociation area: 882.2 Å2
Dissociation energy (ΔGdiss): 8.13 kcal/mol
Dissociation entropy (TΔSdiss): 9.62 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-246992
Assembly 2
Download    3D Visualisation
Assembly Name: C-Jun-amino-terminal kinase-interacting protein 2
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 6906.02 Å2
Buried surface area: 1755.44 Å2
Dissociation area: 877.72 Å2
Dissociation energy (ΔGdiss): 7.95 kcal/mol
Dissociation entropy (TΔSdiss): 10.13 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-246993

Macromolecules

C-Jun-amino-terminal kinase-interacting protein 2
Chains: A, B, C
Length: 63 amino acids
Theoretical weight: 7.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q13387 (Residues: 605-665; Coverage: 7%)
Gene names: IB2, JIP2, MAPK8IP2, PRKM8IPL
Pfam: Variant SH3 domain
C-Jun-amino-terminal kinase-interacting protein 2 in PDB entry 8rpp, assembly 1, front view.
C-Jun-amino-terminal kinase-interacting protein 2 in PDB entry 8rpp, assembly 1, side view.
C-Jun-amino-terminal kinase-interacting protein 2 in PDB entry 8rpp, assembly 1, top view.
Molecule details ›

Search similar proteins

C-Jun-amino-terminal kinase-interacting protein 1
Chain: D
Length: 61 amino acids
Theoretical weight: 7.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UQF2 (Residues: 490-547; Coverage: 8%)
Gene names: IB1, JIP1, MAPK8IP1, PRKM8IP
Pfam: Variant SH3 domain
C-Jun-amino-terminal kinase-interacting protein 1 in PDB entry 8rpp, assembly 1, front view.
C-Jun-amino-terminal kinase-interacting protein 1 in PDB entry 8rpp, assembly 1, side view.
C-Jun-amino-terminal kinase-interacting protein 1 in PDB entry 8rpp, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links