EC 2.7.7.86: Cyclic GMP-AMP synthase
Reaction catalysed:
(1a) ATP + GTP = pppG-P(2'-5')A + diphosphate
Systematic name:
ATP:GTP adenylyltransferase (cyclizing)
Alternative Name(s):
- CGAMP synthase
- CGAS
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Protein families (Pfam)![The deposited structure of PDB entry 8shu contains 1 copy of Pfam domain PF20266 (Mab-21 protein HhH/H2TH-like domain) in Cyclic GMP-AMP synthase. Showing 1 copy in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/8shu_1_C_Pfam_PF20266_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>8shu</span> contains 1 copy of Pfam domain <span class='highlight'>PF20266 (Mab-21 protein HhH/H2TH-like domain)</span> in <span class='highlight'>Cyclic GMP-AMP synthase</span>. Showing 1 copy in chain <span class='highlight'>A [auth C]</span>.")
![The deposited structure of PDB entry 8shu contains 1 copy of Pfam domain PF03281 (Mab-21 protein nucleotidyltransferase domain) in Cyclic GMP-AMP synthase. Showing 1 copy in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/8shu_1_C_Pfam_PF03281_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>8shu</span> contains 1 copy of Pfam domain <span class='highlight'>PF03281 (Mab-21 protein nucleotidyltransferase domain)</span> in <span class='highlight'>Cyclic GMP-AMP synthase</span>. Showing 1 copy in chain <span class='highlight'>A [auth C]</span>.")