Function and Biology

The 2alpha3beta stoichiometry of full-length human alpha4beta2 nicotinic acetylcholine receptor in complex with acetylcholine

Sequence families

Pfam Protein families (Pfam)
PF02932
Domain description: Neurotransmitter-gated ion-channel transmembrane region
Occurring in:
  1. Neuronal acetylcholine receptor subunit alpha-4
  2. Neuronal acetylcholine receptor subunit beta-2
The deposited structure of PDB entry 8st0 contains 2 copies of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Neuronal acetylcholine receptor subunit alpha-4. Showing 1 copy in chain A.
The deposited structure of PDB entry 8st0 contains 3 copies of Pfam domain PF02932 (Neurotransmitter-gated ion-channel transmembrane region) in Neuronal acetylcholine receptor subunit beta-2. Showing 1 copy in chain B.

PF02931
Domain description: Neurotransmitter-gated ion-channel ligand binding domain
Occurring in:
  1. Neuronal acetylcholine receptor subunit alpha-4
  2. Neuronal acetylcholine receptor subunit beta-2
The deposited structure of PDB entry 8st0 contains 2 copies of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Neuronal acetylcholine receptor subunit alpha-4. Showing 1 copy in chain A.
The deposited structure of PDB entry 8st0 contains 3 copies of Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) in Neuronal acetylcholine receptor subunit beta-2. Showing 1 copy in chain B.